DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tak1 and DSTYK

DIOPT Version :9

Sequence 1:NP_524080.1 Gene:Tak1 / 39659 FlyBaseID:FBgn0026323 Length:678 Species:Drosophila melanogaster
Sequence 2:NP_056190.1 Gene:DSTYK / 25778 HGNCID:29043 Length:929 Species:Homo sapiens


Alignment Length:273 Identity:77/273 - (28%)
Similarity:123/273 - (45%) Gaps:32/273 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 LREKVGHGSYGVV--CKAVWRDKLVAVKEFFASAEQK---DIEKEVKQL-SRVKHPNIIALHG-I 78
            |.:::|.|.||||  |.. |........:.....::|   |:..|...: |..||..::.||| :
Human   654 LGQELGRGQYGVVYLCDN-WGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSV 717

  Fly    79 SSYQQ------ATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLI 137
            ..|..      |..||||     .||..|:..:|...:|...:..|....||:.:||:   :.|:
Human   718 IDYNYGGGSSIAVLLIME-----RLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHS---QGLV 774

  Fly   138 HRDVKPLNLLLTNKGRNLKICDFGTVADKSTMMTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIV 202
            |||:|..|:||..:.| .||.|.|....::.|..:..|:...||||:|.| ||....|::::.|:
Human   775 HRDIKLKNVLLDKQNR-AKITDLGFCKPEAMMSGSIVGTPIHMAPELFTG-KYDNSVDVYAFGIL 837

  Fly   203 LWEVLSRK----QPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSM--- 260
            .|.:.|..    :.|:...:...:...:.:|.||..|....:....||.|||...|..||.:   
Human   838 FWYICSGSVKLPEAFERCASKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPLKRPLLGIV 902

  Fly   261 -QYIVGVMHEIVK 272
             ..:.|:|:.:.|
Human   903 QPMLQGIMNRLCK 915

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tak1NP_524080.1 TyrKc 19..264 CDD:197581 74/263 (28%)
STKc_TAK1 25..275 CDD:270960 76/269 (28%)
DSTYKNP_056190.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
PKc_Dusty 651..912 CDD:270877 76/268 (28%)
S_TKc 653..897 CDD:214567 72/253 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0192
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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