DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tak1 and Dstyk

DIOPT Version :9

Sequence 1:	NP_524080.1	Gene:	Tak1 / 39659	FlyBaseID:	FBgn0026323	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_766104.2	Gene:	Dstyk / 213452	MGIID:	1925064	Length:	927	Species:	Mus musculus

Alignment Length:	269	Identity:	75/269 - (27%)
Similarity:	123/269 - (45%)	Gaps:	32/269 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LREKVGHGSYGVV--CKAVWRDKLVAVKEFFASAEQK---DIEKEVKQL-SRVKHPNIIALHG-I 78
            |.:::|.|.||||  |.. |........:.....::|   |:..|...: |..||..::.||| :
Mouse   652 LGQELGRGQYGVVYLCDN-WGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSV 715

  Fly    79 SSYQQ------ATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLI 137
            ..|..      |..||||     .||..|:..:|...:|...:..|....||:.:||:   :.|:
Mouse   716 IDYNYGGGSSVAVLLIME-----RLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHS---QGLV 772

  Fly   138 HRDVKPLNLLLTNKGRNLKICDFGTVADKSTMMTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIV 202
            |||:|..|:||..:.| .||.|.|....::.|..:..|:...||||:|.| ||....|::::.|:
Mouse   773 HRDIKLKNVLLDKQNR-AKITDLGFCKPEAMMSGSIVGTPIHMAPELFTG-KYDNSVDVYAFGIL 835

  Fly   203 LWEVLSRK----QPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYI 263
            .|.:.|..    :.|:...:...:...:.:|.||..|....:....||.|||...|..||    :
Mouse   836 FWYICSGSIKLPEAFERCASKDHLWNNVRRGTRPERLPVFDEECWQLMEACWDGDPLKRP----L 896

  Fly   264 VGVMHEIVK 272
            :|::..:::
Mouse   897 LGIVQPMLR 905

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tak1	NP_524080.1	TyrKc	19..264	CDD:197581	74/259 (29%)
Tak1	NP_524080.1	STKc_TAK1	25..275	CDD:270960	74/265 (28%)
Dstyk	NP_766104.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		PKc_Dusty	649..910	CDD:270877	75/269 (28%)
		S_TKc	651..895	CDD:214567	72/253 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900