DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tak1 and F57B9.8

DIOPT Version :9

Sequence 1:	NP_524080.1	Gene:	Tak1 / 39659	FlyBaseID:	FBgn0026323	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_498511.1	Gene:	F57B9.8 / 175967	WormBaseID:	WBGene00018999	Length:	444	Species:	Caenorhabditis elegans

Alignment Length:	346	Identity:	87/346 - (25%)
Similarity:	161/346 - (46%)	Gaps:	58/346 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 QAAYVDFSEITLREKVGHGSYGVVCKAVWRDKL-----------VAVK----EFFASAEQKDIEK 59
            |:..::.::||:.:.:|.|::|.|       ||           ||:|    |.....:.|:|..
Worm   106 QSWELNHADITMTKVLGEGAFGEV-------KLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIIT 163

  Fly    60 EVKQLSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWAR----- 119
            |.:.:....|.|::..:|:::..:...::||...||:|..:|...        .::.|..
Worm   164 EARLMRGFDHKNVVKCYGVAAIDEPLLVVMELVPGGALDKYLQKN--------SSVQWPEKLDII 220

  Fly   120 -QCAEGLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNL-KICDFG--TVADKSTMMTNNRGSAAWM 180
             |.|.||||:|:   |.:||||:...|:|.   |:.: |:.|||  .|..:..|..:.|....|:
Worm   221 AQVAAGLAYIHS---KNIIHRDIAARNILY---GKGVAKVSDFGLSRVGTEYQMDPSKRVPIRWL 279

  Fly   181 APEVFEGSKYTEKCDIFSWAIVLWEVLSR-KQPFKGIDNAYTIQWKIYKGE-RPPLLTTCPKRIE 243
            :||......||.:.|:|:::|:.|||:.. .||:..: ....:..|:.:.: |.|:....|..:.
Worm   280 SPETIVSFLYTPQTDVFAFSILCWEVIENGAQPYPEM-LVVQVHQKVGRDDYRMPISQKAPAMLA 343

  Fly   244 DLMTACWKTVPEDRPSMQYIVGVMHEIV--KDYTGADKALEYTFVNQQIVTKESDGTVAAQPDSL 306
            |::..||...|:.||:|..:|.:|:||.  ||.|..:|:     ..|......|.|.::   |.:
Worm   344 DVIKKCWIRDPQQRPTMSQVVQMMYEITGKKDKTSVNKS-----TGQLRAKMMSTGPMS---DPM 400

  Fly   307 SSQEGELSPSSTQLTPTTAAN 327
            ..:..:.:....:..|::|:|
Worm   401 RDKTAKKTGRRNKKKPSSASN 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tak1	NP_524080.1	TyrKc	19..264	CDD:197581	71/270 (26%)
Tak1	NP_524080.1	STKc_TAK1	25..275	CDD:270960	75/277 (27%)
F57B9.8	NP_498511.1	SH2_Fps_family	1..91	CDD:198224
		STYKc	115..367	CDD:214568	72/273 (26%)
		PTKc	119..367	CDD:270623	70/269 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000