DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tak1 and sel-15

DIOPT Version :9

Sequence 1:NP_524080.1 Gene:Tak1 / 39659 FlyBaseID:FBgn0026323 Length:678 Species:Drosophila melanogaster
Sequence 2:NP_001366799.1 Gene:sel-15 / 175225 WormBaseID:WBGene00016030 Length:847 Species:Caenorhabditis elegans


Alignment Length:364 Identity:116/364 - (31%)
Similarity:173/364 - (47%) Gaps:59/364 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 ASLDALQAA-----YVDFSEITLREKVGHGSYGVVCKAVWRDKLVAVKEFFASA-----EQKDIE 58
            |.|..|::|     ::..:||..:|.:|.||:|.|.|..:|.||||||.:.|.|     |...:.
 Worm   496 ADLLQLRSALPAPFHLCLAEIEFQESIGSGSFGKVYKGTYRGKLVAVKRYRAMAFGCKSETDMLC 560

  Fly    59 KEVKQLSRVKHPNIIALHGISSYQQATY-LIMEFAEGGSLHNFLHGK---VKPAYSLAHAMSWAR 119
            :||..|||:.|||::|..|.|....:.: :|.||.|.|||...||.:   :.||:.|..::..||
 Worm   561 REVSILSRLAHPNVVAFVGTSLDDPSQFAIITEFVENGSLFRLLHEEKRVMDPAFRLRISLDVAR 625

  Fly   120 QCAEGLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFG----TVADKSTMMTNNRGSAAWM 180
                |:.|||....||:||||:...|:|:...||:: :.|||    ....:...:|...|:..||
 Worm   626 ----GMRYLHESAAKPVIHRDLNSHNILIHADGRSV-VADFGESRFVCQREDENLTKQPGNLRWM 685

  Fly   181 APEVF-EGSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPL----LTTCPK 240
            ||||| :..||..|.|:||:|:|:||:.:.:.||..:..|.......||..||.|    ....|.
 Worm   686 APEVFSQSGKYDRKVDVFSFALVIWEIHTAELPFSHLKPAAAAAEMTYKRGRPTLPNQPTAQFPA 750

  Fly   241 RIEDLMTACWKTVPEDRPSMQYIVGVMHEIVKDYTGADKALEYTFVNQQIVTKESDGTVAAQPDS 305
            .|..|:...|......||....||.::...|                      ||..|..:.|.:
 Worm   751 HILSLIPQAWHPESSSRPDFVEIVALLEPHV----------------------ESTHTDISAPST 793

  Fly   306 ---LSSQEGELS---PSSTQLTPTTAANANVNAIAISKT 338
               |:||..:||   |.:::..|..:|   ::.||.:.|
 Worm   794 VSQLTSQWEQLSVAPPPASKFPPILSA---LHGIAATGT 829

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tak1NP_524080.1 TyrKc 19..264 CDD:197581 93/262 (35%)
STKc_TAK1 25..275 CDD:270960 94/267 (35%)
sel-15NP_001366799.1 ANKYR 3..217 CDD:223738
ANK repeat 115..147 CDD:293786
PHA03095 128..>388 CDD:222980
ANK repeat 153..180 CDD:293786
ANK repeat 182..213 CDD:293786
ANK repeat 215..246 CDD:293786
ANK repeat 285..318 CDD:293786
ANK repeat 320..353 CDD:293786
ANKYR <323..458 CDD:223738
ANK repeat 355..380 CDD:293786
PKc_TNNI3K 522..780 CDD:270966 93/262 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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