Protein Alignment Tak1 and hck

DIOPT Version :10

• Sequence 1: NP_524080.1
• Gene: Tak1 / 39659
• FlyBaseID: FBgn0026323
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_005174178.1
• Gene: hck / 101885596
• ZFINID: ZDB-GENE-090313-72
• Length: 499
• Species: Danio rerio
• Alignment Length: 271
• Identity: 80/271 - (29%)
• Similarity: 140/271 - (51%)
• Gaps: 23/271 - (8%)

  Fly    19 ITLREKVGHGSYGVVCKAVW-RDKLVAVKEFF-ASAEQKDIEKEVKQLSRVKHPNIIALHGISSY 81
            :.|.:::|.|.:|.|..|:: :...||||... .|...:....|...:..::|..::.|:.:.:.
Zfish   234 LKLDKRLGAGQFGEVWMAMYNKHTKVAVKTMKPGSMSVEAFLMEANLMKSLQHDKLVRLNAVVTK 298

  Fly    82 QQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHRDVKPLNL 146
            ::..|:|.||.|.|||.:|:.........|...:.::.|.|||:||:.   .:..||||::..|:
Zfish   299 EEPIYIITEFMEKGSLLDFIKSDEGNRVQLPKLIDFSAQIAEGMAYIE---QRNYIHRDLRAANI 360

  Fly   147 LLTNKGRNLKICDFGTVADKSTMMTNNRGSA--------AWMAPEVFEGSKYTEKCDIFSWAIVL 203
            |: ||....||.|||.    :.::.:|..:|        .|.|||......:|.|.|::|:.|:|
Zfish   361 LV-NKSLVCKIADFGL----ARIIEDNEYTAREGAKFPIKWTAPEAINYGSFTIKSDVWSFGILL 420

  Fly   204 WEVLS-RKQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVM 267
            .|::| .:.|:.|:.|...|: .:.:|.|...|.:||:.:.|:|..|||..|||||:.:|:..|:
Zfish   421 TEIISYGRTPYPGMTNPEVIR-ALERGYRMQRLDSCPQELYDIMLECWKNKPEDRPTFEYLQSVL 484

  Fly   268 HEIVKDYTGAD 278
            .:.   ||..:
Zfish   485 EDF---YTATE 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tak1	NP_524080.1	STKc_TAK1	25..275	CDD:270960	77/260 (30%)
hck	XP_005174178.1	SH3	58..109	CDD:473055
		SH2	113..215	CDD:472789
		PTKc_Hck	222..487	CDD:270658	78/261 (30%)