Protein Alignment CG6888 and PRDX6

DIOPT Version :9

• Sequence 1: NP_648759.1
• Gene: CG6888 / 39658
• FlyBaseID: FBgn0036490
• Length: 196
• Species: Drosophila melanogaster
• Sequence 2: NP_004896.1
• Gene: PRDX6 / 9588
• HGNCID: 16753
• Length: 224
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 60/197 - (30%)
• Similarity: 96/197 - (48%)
• Gaps: 14/197 - (7%)

  Fly     4 LNINQVAPNFTTNAVVSG-GYRNFALTDLRGRYVLLVFYPADFSYVCPTELQAFSDRAPEFRNVG 67
            |.:..|||||..|..|.. .:.:| |.|..|   :|..:|.||:.||.|||...:..||||....
Human     5 LLLGDVAPNFEANTTVGRIRFHDF-LGDSWG---ILFSHPRDFTPVCTTELGRAAKLAPEFAKRN 65

  Fly    68 CEVLACSTDSHFVHCAW---MNTPRKNGGLGELDIPLLADKNMKIARDYGVLD----EDTGLAL- 124
            .:::|.|.||...|.||   :|.........:|..|::.|:|.::|...|:||    ::.|:.:
Human    66 VKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKGMPVT 130

  Fly   125 -RALFIIDREGRIRQITVNDMGVGRSVDEALRLVQAFQFSDEFGEVCPVNWRPGAKTMKADATGK 188
             |.:|:...:.:::...:.....||:.||.||:|.:.|.:.|.....||:|:.|...|......:
Human   131 ARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKDGDSVMVLPTIPE 195

  Fly   189 EE 190
            ||
Human   196 EE 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6888	NP_648759.1	AhpC	3..194	CDD:223527	60/197 (30%)
		PRX_Typ2cys	6..177	CDD:239313	55/180 (31%)
PRDX6	NP_004896.1	PRX_1cys	7..222	CDD:239314	59/195 (30%)
		Required and sufficient for targeting to lysosomes and lamellar bodies. /evidence=ECO:0000250|UniProtKB:O35244	31..40		3/11 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.710