DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6888 and TSA1

DIOPT Version :9

Sequence 1:	NP_648759.1	Gene:	CG6888 / 39658	FlyBaseID:	FBgn0036490	Length:	196	Species:	Drosophila melanogaster
Sequence 2:	NP_013684.1	Gene:	TSA1 / 854980	SGDID:	S000004490	Length:	196	Species:	Saccharomyces cerevisiae

Alignment Length:	190	Identity:	101/190 - (53%)
Similarity:	132/190 - (69%)	Gaps:	0/190 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 INQVAPNFTTNAVVSGGYRNFALTDLRGRYVLLVFYPADFSYVCPTELQAFSDRAPEFRNVGCEV 70
            :.:.||.|...|||.|.:...:|...:|:||:|.|.|..|::|||||:.|||:.|.:|...|.:|
Yeast     5 VQKQAPTFKKTAVVDGVFDEVSLDKYKGKYVVLAFIPLAFTFVCPTEIIAFSEAAKKFEEQGAQV 69

  Fly    71 LACSTDSHFVHCAWMNTPRKNGGLGELDIPLLADKNMKIARDYGVLDEDTGLALRALFIIDREGR 135
            |..||||.:...||.|.|||.||||.::||||||.|..::||||||.|:.|:|||.|||||.:|.
Yeast    70 LFASTDSEYSLLAWTNIPRKEGGLGPINIPLLADTNHSLSRDYGVLIEEEGVALRGLFIIDPKGV 134

  Fly   136 IRQITVNDMGVGRSVDEALRLVQAFQFSDEFGEVCPVNWRPGAKTMKADATGKEEYFKHA 195
            ||.||:||:.|||:||||||||:|||::|:.|.|.|.||.|||.|:|......:|||:.|
Yeast   135 IRHITINDLPVGRNVDEALRLVEAFQWTDKNGTVLPCNWTPGAATIKPTVEDSKEYFEAA 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6888	NP_648759.1	AhpC	3..194	CDD:223527	100/187 (53%)
CG6888	NP_648759.1	PRX_Typ2cys	6..177	CDD:239313	92/170 (54%)
TSA1	NP_013684.1	PRX_Typ2cys	5..176	CDD:239313	92/170 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346739
Domainoid	1	1.000	161	1.000	Domainoid score	I848
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I706
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54000
OrthoFinder	1	1.000	-	-		FOG0000434
OrthoInspector	1	1.000	-	-		mtm9201
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	O	PTHR10681
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X272
TreeFam	1	0.960	-	-
	12	11.760