Protein Alignment CG7011 and ERGIC1

DIOPT Version :10

• Sequence 1: NP_648758.1
• Gene: CG7011 / 39657
• FlyBaseID: FBgn0036489
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: XP_011532899.1
• Gene: ERGIC1 / 57222
• HGNCID: 29205
• Length: 314
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 98/375 - (26%)
• Similarity: 150/375 - (40%)
• Gaps: 103/375 - (27%)

  Fly     9 RLDAYPRTLDDFSVRTVGGAAVTIISTSIISLLIFLEVLNYMQPTLNEELFV-DTTRDH--KLRI 70
            :.|.|.:...|.:..|..||.::|.....|..|...|:..::...:..||:| |..:|.  |:.:
Human    31 KFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDSGGKIDV 95

  Fly    71 NLDVTLHNLACNYISLDAMDSSGDTHLRVDHDVFKHRLDLNGEPLKETPIKEIVAVSPPNKNVTC 135
            :|:::|.||.|..:.||..|..|
Human    96 SLNISLPNLHCELVGLDIQDEMG------------------------------------------ 118

  Fly   136 GSCYGAEHNATHCCNTCEDVLDAYRLRKWTVAVDKIEQCKGKYKRSDEDAFKEGCRIQGHLEVNR 200
                  .|...|..|:.                 ||....|           .|||.:|...:|:
Human   119 ------RHEVGHIDNSM-----------------KIPLNNG-----------AGCRFEGQFSINK 149

  Fly   201 MAGSFHFAPGKSFSIRQFHIHDFQFSNVKLSHTINHLSFGEKIEFAKTH----PLDGLRVD-VAE 260
            :.|:||.:.         |....|..|..::|.|:.||||:.::....|    .|.|  .| :..
Human   150 VPGNFHVST---------HSATAQPQNPDMTHVIHKLSFGDTLQVQNIHGAFNALGG--ADRLTS 203

  Fly   261 TKSEMFNYYLKIVPTLYMRGNSDGEPIYTNQFSVTRYRKD---LSDRERGMPGIFFSYELSPLMV 322
            ......:|.||||||:|  .:..|:..|:.|::|.  .|:   .|...|.:|.|:|.|:|||:.|
Human   204 NPLASHDYILKIVPTVY--EDKSGKQRYSYQYTVA--NKEYVAYSHTGRIIPAIWFRYDLSPITV 264

  Fly   323 KYAERHSSFGHFATNCCSIIGGVFTVAGILAVLLNNSWEAIQRKLEVGKL 372
            ||.||......|.|..|:||||.|||||||...:..:.|| .:|:::||:
Human   265 KYTERRQPLYRFITTICAIIGGTFTVAGILDSCIFTASEA-WKKIQLGKM 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7011	NP_648758.1	ERGIC_N	7..97	CDD:464000	25/90 (28%)
		COPIIcoated_ERV	138..352	CDD:462327	66/221 (30%)
ERGIC1	XP_011532899.1	ERGIC_N	31..122	CDD:464000	26/138 (19%)
		COPIIcoated_ERV	128..295	CDD:462327	64/209 (31%)