DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prp31 and emb1220

DIOPT Version :9

Sequence 1:	NP_648756.1	Gene:	Prp31 / 39655	FlyBaseID:	FBgn0036487	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_564754.1	Gene:	emb1220 / 842312	AraportID:	AT1G60170	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	503	Identity:	224/503 - (44%)
Similarity:	311/503 - (61%)	Gaps:	37/503 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLADELLADLEEDNDNEL-----------EEEDSEMASAEDESLLAEKLAKPAPNLMDVDVTVQS 55
            :|.|..||||:|.:|||.           ||||.:|..|:.|:|          |..|:|
plant     3 TLEDSFLADLDELSDNEAELDENDGDVGKEEEDVDMDMADLETL----------NYDDLD----- 52

  Fly    56 VRELCKLRDSERLKNTLQQIEHYASRQRTAAEMLGSVESDPEYCLIVDANAIAVDIDNEISIVHK 120
              .:.||:.|:|..:.:.::|....:....||....:|.||||.||||.|.::|||:|||.|||.
plant    53 --NVSKLQKSQRYADIMHKVEEALGKDSDGAEKGTVLEDDPEYKLIVDCNQLSVDIENEIVIVHN 115

  Fly   121 FTKEKYQKRFPELDSLIVGEIEYLLAVKELGNDLDQVKNNEKLQAILTQATIMIVSVTASTTQGT 185
            |.|:||:.:|.||:||:...|:|...||::||:.|....:  |..:|..|.||:|||||.||:|:
plant   116 FIKDKYKLKFQELESLVHHPIDYACVVKKIGNETDLALVD--LADLLPSAIIMVVSVTALTTKGS 178

  Fly   186 MLTPAEKAKIDEACEMAIELNNFKSKIYEYVESRMTFIAPNLSMIVGASTAAKLLGIAGGLSKLS 250
            .|......|:.|||:.|::|::.:.|:.|:|||:|..||||||.|||::.||||:|.|||||.|:
plant   179 ALPEDVLQKVLEACDRALDLDSARKKVLEFVESKMGSIAPNLSAIVGSAVAAKLMGTAGGLSALA 243

  Fly   251 KMPACNVQVLGAQKKTLSGFSQTQMLPHTGYVYYSQIVQDTAPDLRRKAARLVAAKSVLAARVDA 315
            |||||||||||.::|.|:|||........||:..::|.|.|.|.|:.:|.|||||||.|||||||
plant   244 KMPACNVQVLGHKRKNLAGFSSATSQSRVGYLEQTEIYQSTPPGLQARAGRLVAAKSTLAARVDA 308

  Fly   316 CHESVHGEIGLRFKEDVEKKLDKLQEPPPVKFIKPLPKPIEGSKKKRGGKRVRKMKERYALTEFR 380
            ......|..|..|:|::.||::|.|||||.:..||||.|....||:|||:|:|||||||.:|:.|
plant   309 TRGDPLGISGKAFREEIRKKIEKWQEPPPARQPKPLPVPDSEPKKRRGGRRLRKMKERYQVTDMR 373

  Fly   381 KQANRMNFGDIEEDAYQGDLGYSRGTIGKTGTGRIRLPQVDEKTKVRISKTLHKNLQKQQVYGGN 445
            |.||||.||..||.:....||...|.:|:.|:.|:|:..|  .:|::|:..:.|.|:::|..||.
plant   374 KLANRMAFGTPEESSLGDGLGEGYGMLGQAGSNRLRVSSV--PSKLKINAKVAKKLKERQYAGGA 436

  Fly   446 TTVKRQISGTASSVAFTPLQGLEIVNPQAAERSQTEANAKYFSNTSGF 493
            ||     ||..||:||||:||:|:.|||.|....:...:.|||.:..|
plant   437 TT-----SGLTSSLAFTPVQGIELCNPQQALGLGSGTQSTYFSESGTF 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prp31	NP_648756.1	NOSIC	101..152	CDD:197999	26/50 (52%)
		Nop	107..337	CDD:280047	115/229 (50%)
		Prp31_C	345..472	CDD:286825	57/126 (45%)
emb1220	NP_564754.1	Nop	103..331	CDD:396390	115/229 (50%)
emb1220	NP_564754.1	Prp31_C	338..458	CDD:401657	57/126 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	215	1.000	Domainoid score	I759
eggNOG	1	0.900	-	-		E1_COG1498
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5980
Inparanoid	1	1.050	385	1.000	Inparanoid score	I516
OMA	1	1.010	-	-		QHG54654
OrthoDB	1	1.010	-	-		D791296at2759
OrthoFinder	1	1.000	-	-		FOG0004373
OrthoInspector	1	1.000	-	-		oto3908
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13904
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.940