Protein Alignment FucTA and FUT6

DIOPT Version :10

• Sequence 1: NP_648754.2
• Gene: FucTA / 39653
• FlyBaseID: FBgn0036485
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_000141.1
• Gene: FUT6 / 2528
• HGNCID: 4017
• Length: 359
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 104/285 - (36%)
• Similarity: 141/285 - (49%)
• Gaps: 34/285 - (11%)

  Fly   205 CELTANRDLASTADMILYKDH---YIPTG--IRRPSNSKQVSMLYYLECPYHTQNVKVPDA-INW 263
            |.:||:|.:...||.::....   |.|:.  .|.|....|..:.:.:|.|.|...:|..|. .|.
Human    90 CNITADRKVYPQADAVIVHHREVMYNPSAQLPRSPRRQGQRWIWFSMESPSHCWQLKAMDGYFNL 154

  Fly   264 TATYRRDSTIVAPY---EKWQYYDTKVQQQEQDINYSVNKTKKVAWFVSNCGARNGRLQYAHELQ 325
            |.:||.||.|..||   |.|     ..|.....:|.|. ||:.|||.|||.|..:.|::|...||
Human   155 TMSYRSDSDIFTPYGWLEPW-----SGQPAHPPLNLSA-KTELVAWAVSNWGPNSARVRYYQSLQ 213

  Fly   326 KYIEVDIYGACGNFKCSRS----TADKCFEILDNDYKFYLAFENSNCKDYITEKFFVNALNRRVL 386
            .:::||:||        ||    ......|.|.. ||||||||||...||||||.:.|||....:
Human   214 AHLKVDVYG--------RSHKPLPQGTMMETLSR-YKFYLAFENSLHPDYITEKLWRNALEAWAV 269

  Fly   387 PIVMGARPEDYEVSAPRRSYIHVDEFSSPKELAEYLRILDHDDELYNSYFKWKGT---GEFINTY 448
            |:|:|....:||...|..::||||:|.|||:||.||:.||.|...|.|||:|:.|   ..|....
Human   270 PVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWAL 334

  Fly   449 YWCRVCATLHNEEQLRK---PRWYT 470
            .:|:.|..|..|.:.:.   ..|:|
Human   335 AFCKACWKLQEESRYQTRGIAAWFT 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FucTA	NP_648754.2	Glyco_tran_10_N	172..278	CDD:465336	25/81 (31%)
		Glyco_transf_10	299..475	CDD:459962	74/182 (41%)
FUT6	NP_000141.1	Glyco_tran_10_N	62..169	CDD:465336	24/78 (31%)
		determines site-specific fucosylation. /evidence=ECO:0000269|PubMed:17604274	73..112		6/21 (29%)
		Glyco_transf_10	185..357	CDD:459962	73/181 (40%)