DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FucTA and FUT3

DIOPT Version :9

Sequence 1:	NP_001261872.1	Gene:	FucTA / 39653	FlyBaseID:	FBgn0036485	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_000140.1	Gene:	FUT3 / 2525	HGNCID:	4014	Length:	361	Species:	Homo sapiens

Alignment Length:	289	Identity:	103/289 - (35%)
Similarity:	144/289 - (49%)	Gaps:	41/289 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 CELTANRDLASTADMILY---------KDHYIPTGIRRPSNSKQVSMLYYLECPYHTQNVKVPDA 260
            |.:||:|.:...||.::.         |....|:  .||...:.:  .:.||.|.:.|:::..|.
Human    91 CHITADRKVYPQADTVIVHHWDIMSNPKSRLPPS--PRPQGQRWI--WFNLEPPPNCQHLEALDR 151

  Fly   261 -INWTATYRRDSTIVAPY---EKWQYYDTKVQQQEQDINYSVNKTKKVAWFVSNCGARNGRLQYA 321
             .|.|.:||.||.|..||   |.|     ..|.....:|.|. ||:.|||.|||....:.|::|.
Human   152 YFNLTMSYRSDSDIFTPYGWLEPW-----SGQPAHPPLNLSA-KTELVAWAVSNWKPDSARVRYY 210

  Fly   322 HELQKYIEVDIYGACGNFKCSRSTADK--CFEILDNDYKFYLAFENSNCKDYITEKFFVNALNRR 384
            ..||.:::||:||.      |.....|  ..|.|.. ||||||||||...||||||.:.|||...
Human   211 QSLQAHLKVDVYGR------SHKPLPKGTMMETLSR-YKFYLAFENSLHPDYITEKLWRNALEAW 268

  Fly   385 VLPIVMGARPEDYEVSAPRRSYIHVDEFSSPKELAEYLRILDHDDELYNSYFKWKGTGEFINTYY 449
            .:|:|:|....:||...|..::||||:|.|||:||.||:.||.|...|.|||:|:.|.. ..::.
Human   269 AVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLR-PRSFS 332

  Fly   450 W----CRVCATLHNEEQLRKPR----WYT 470
            |    |:.|..|..|.:.:..|    |:|
Human   333 WALDFCKACWKLQQESRYQTVRSIAAWFT 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FucTA	NP_001261872.1	Glyco_tran_10_N	173..277	CDD:293644	22/81 (27%)
FucTA	NP_001261872.1	Glyco_transf_10	300..473	CDD:279224	74/181 (41%)
FUT3	NP_000140.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..58
		Glyco_tran_10_N	60..170	CDD:407214	23/82 (28%)
		Glyco_transf_10	189..357	CDD:395683	72/175 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	123	1.000	Domainoid score	I5576
eggNOG	1	0.900	-	-		E1_KOG2619
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4402
Isobase	1	0.950	-	0	Normalized mean entropy	S6520
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394490at33208
OrthoFinder	1	1.000	-	-		FOG0000215
OrthoInspector	1	1.000	-	-		mtm8516
orthoMCL	1	0.900	-	-		OOG6_100170
Panther	1	1.100	-	-	O	PTHR11929
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3232
SonicParanoid	1	1.000	-	-		X114
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.810