DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex3 and pex3

DIOPT Version :9

Sequence 1:	NP_001261871.1	Gene:	Pex3 / 39652	FlyBaseID:	FBgn0036484	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_956522.1	Gene:	pex3 / 393197	ZFINID:	ZDB-GENE-040426-979	Length:	364	Species:	Danio rerio

Alignment Length:	402	Identity:	132/402 - (32%)
Similarity:	212/402 - (52%)	Gaps:	62/402 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLSRLQDFLSRHRRKFIVTGVLVGGTIFAARYAQRRFVEFQEKQAREFFERTRRTTHFESTEKTC 65
            |||...:|:.||:||||.|||.|||.....:||||:..|.||::|.|:..:.||..||||.::||
Zfish     1 MLSSTWNFIKRHKRKFIFTGVFVGGVYLLGKYAQRKIQEMQEREAAEYIAQARRQFHFESNQRTC 65

  Fly    66 NQVILGMGEEMCQAVLRECSTDELLEQLRQNPKNKLELWEDMKIVAFTRLATYVYASSMLVIALR 130
            |..:|.|...:.:|::...:::.|...|:..|.||||:|||:||::|||....||::.|||:.||
Zfish    66 NMTVLSMLPTLREAIIHHLNSESLTTLLKTKPANKLEIWEDLKIISFTRSIVAVYSTCMLVVLLR 130

  Fly   131 VQLNLLGGYIYRDIMTEQKQVT----DELKQQYLSLIRHFITDSGIRDLARYIRTQVIAVTKTIP 191
            ||||::|||:|.|....:..:|    .:::|||||.|:|.:.: |:.:|...::..|..|...:.
Zfish   131 VQLNIIGGYLYLDNSVTKNGMTPLAPPDVQQQYLSSIQHLLGE-GLMELITVVKKAVQEVFGLVS 194

  Fly   192 LSEQLSLSDLEQLFWSLQMAINADTRRDPNSRMSKYLLPSQN----------PSHSPLLQKMVNE 246
            |.:.|||.:|||....::..:..|:.:  ...:|.|::|.:.          ..:.....|::||
Zfish   195 LKQSLSLQELEQQLTQIRQLVEDDSSK--YKGLSWYMMPDEENTLASQACGLTENDVTTIKLLNE 257

  Fly   247 TLDLLESEDAVGVCSHNVSRGFVLACDAIAESMGETLQHLPQAKVQTQQEQSVKFNQAGSLGAST 311
            |.|:|||.|...|....::||||...|.:||..                    :..|..|..:||
Zfish   258 TRDMLESPDFNIVLHTCLNRGFVRFLDNMAEFF--------------------RPPQRDSTPSST 302

  Fly   312 SKSQNGLENNNLLNINRVLLALAKLIPIISGLTSRGFDTTSRPHNLPTQLLTFYV----VAEKTK 372
            ..           .::.|.|.|||:||||:|          :.|::.:::.:.:|    :.::.|
Zfish   303 PD-----------QLSHVSLPLAKIIPIING----------QIHSICSEIPSHFVQDLLLIDQVK 346

  Fly   373 TLGANVYESFSS 384
            ...|||||:||:
Zfish   347 EFAANVYETFST 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex3	NP_001261871.1	Peroxin-3	11..268	CDD:282706	98/270 (36%)
pex3	NP_956522.1	Peroxin-3	11..353	CDD:282706	123/385 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8314
eggNOG	1	0.900	-	-		E1_KOG4444
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2691
Inparanoid	1	1.050	207	1.000	Inparanoid score	I3681
OMA	1	1.010	-	-		QHG56127
OrthoDB	1	1.010	-	-		D381303at33208
OrthoFinder	1	1.000	-	-		FOG0004280
OrthoInspector	1	1.000	-	-		oto40534
orthoMCL	1	0.900	-	-		OOG6_103586
Panther	1	1.100	-	-	LDO	PTHR28080
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3683
SonicParanoid	1	1.000	-	-		X4649
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870