DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex3 and prx-3

DIOPT Version :9

Sequence 1:	NP_001261871.1	Gene:	Pex3 / 39652	FlyBaseID:	FBgn0036484	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001123111.1	Gene:	prx-3 / 182644	WormBaseID:	WBGene00004193	Length:	353	Species:	Caenorhabditis elegans

Alignment Length:	327	Identity:	70/327 - (21%)
Similarity:	138/327 - (42%)	Gaps:	51/327 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLSRLQDFLSRHRRKFIVTGVLVGGTIFAARYAQRRFVEFQEKQAREFFERTRRTTHFESTEKTC 65
            ||:...:|..|::.|.|..|||||..|...:.:.|.....:...:.|...:.||...|:||.::|
Worm     1 MLASAWEFAKRNKGKIIAGGVLVGSAIAYVQSSSRPKTLEKVSTSSELPNQARRHYIFDSTHRSC 65

  Fly    66 NQVILGMGEEMCQAVLRECSTDELLEQLRQNP----KNKLELWEDMKIVAFTRLATYVYASSMLV 126
            :|.|..:...:...:......:.:.|:|:..|    :.|::|||.:|..||.|:.:..:..|:|.
Worm    66 DQSITDLIPSIVTQIQARFDVESIQEKLQNTPDLTAEQKMQLWEQLKKNAFCRIVSVAFGFSILT 130

  Fly   127 IALRVQLNLLG-----------------GYIYRDI--MTEQKQVTDEL-----------KQQYLS 161
            :.|:.|:::|.                 .||...:  |...:..::.|           ::.:|.
Worm   131 LTLKAQISILAADTCSQFEQRNKKPTWQNYIPESMNSMWNSRTGSNGLSPTDNPMDVGNRRIFLQ 195

  Fly   162 LIRHFITDSGIRDLARYIRTQVIAVTKTIPLSEQLSLSDLEQLFWSLQMAINADTRRDPNSRMSK 226
            .:::| |..||.:|..|:...:....:...|::..|.:::...|..:...|:.      |..::|
Worm   196 CVQYF-TLRGIPELMEYVAEAIPNELQNWKLTDIKSKTEMRDFFDRVSYRISF------NGLLTK 253

  Fly   227 YLLP----SQNPSHS--PLLQKMVNETLDLLESEDAVGVCSHNVSRGFVLACDAIAESMGETLQH 285
            .:.|    .|:.|.|  .||||:...    |||..::.|.:..:...|..|...:.......:::
Worm   254 LVAPLDGDGQDNSSSVMKLLQKLTTN----LESSKSIHVLNSLLDFYFSAALKMVENDEQPLVKY 314

  Fly   286 LP 287
            :|
Worm   315 VP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex3	NP_001261871.1	Peroxin-3	11..268	CDD:282706	64/296 (22%)
prx-3	NP_001123111.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56127
OrthoDB	1	1.010	-	-		D381303at33208
OrthoFinder	1	1.000	-	-		FOG0004280
OrthoInspector	1	1.000	-	-		oto19360
orthoMCL	1	0.900	-	-		OOG6_103586
Panther	1	1.100	-	-	LDO	PTHR28080
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3683
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.960