DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdi and PDIL5-2

DIOPT Version :9

Sequence 1:	NP_001287070.1	Gene:	Pdi / 39651	FlyBaseID:	FBgn0286818	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_564462.1	Gene:	PDIL5-2 / 840461	AraportID:	AT1G35620	Length:	440	Species:	Arabidopsis thaliana

Alignment Length:	388	Identity:	103/388 - (26%)
Similarity:	170/388 - (43%)	Gaps:	64/388 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFLICAL-FLAASY-VAASAEAEVKVEEGVLVATVDNFKQLIADNEFVLVEFYAPWCGHCKALA 63
            :|.|:|.: ||..|. ::||::.:..::..||..|..||...|:..:.:.|:||||||||||.|.
plant     4 LKLLLCWISFLTLSISISASSDDQFTLDGTVLELTDSNFDSAISTFDCIFVDFYAPWCGHCKRLN 68

  Fly    64 PEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAW 128
            ||...||..||:.:.||.:||::|.....||.:..:..:|||..:..|.|:||.|.|:|..::.:
plant    69 PELDAAAPILAKLKQPIVIAKLNADKYSRLARKIEIDAFPTLMLYNHGVPMEYYGPRKADLLVRY 133

  Fly   129 VTKKTGPPAKDLTSVADAEQFLKD-------------NEIAIIGFFKDLESEEAKTFTKVANALD 180
            :.|...|....|.|.:..::|::|             ||..|.|.        .:.:.|.|
plant   134 LKKFVAPDVAVLESDSTVKEFVEDAGTFFPVFIGFGLNESIISGL--------GRKYKKKA---- 186

  Fly   181 SFVFGVSS--NADVIAKYE-AKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPLIVDFNH 242
              .|.||.  :.|.:..|: .|...:|...|..::.|||.|...:..|::|.:...||||:..||
plant   187 --WFAVSKEVSEDTMVSYDFDKAPALVANHPTYNEHSVFYGPFEDGFLEEFVKQSFLPLILPINH 249

  Fly   243 ESASKIFGGSIKSHLLFFVSREGGHIEKYVDPLKEIAKKYRDDIL-FVTISSDEEDHTRIFEFFG 306
            ::...:.....|..|..........:||....|:..|...||.:. :|.:...||    ..:.|.
plant   250 DTLKLLKDDERKIVLTIVEDETHESLEKLYKALRAAAHANRDLVFGYVGVKQFEE----FVDSFH 310

  Fly   307 MNK----------------EEVPTIRLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDGKLKQ 353
            ::|                ::|..|..|..|||           ....:..||:.:.:|:.::
plant   311 VDKKTNLPKIVVWDGDEEYDQVTGIETITQEED-----------HLTQVSRFLEGYREGRTEK 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_001287070.1	ER_PDI_fam	27..474	CDD:273457	95/360 (26%)
		pdi_dom	33..133	CDD:273454	40/99 (40%)
		PDI_b_family	137..231	CDD:239279	24/109 (22%)
		PDI_b'_family	244..347	CDD:239280	21/119 (18%)
		PDI_a_PDI_a'_C	368..469	CDD:239293
PDIL5-2	NP_564462.1	ER_PDI_fam	34..>327	CDD:273457	86/310 (28%)
PDIL5-2	NP_564462.1	PDI_a_family	35..134	CDD:239259	40/98 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810