DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdi and Tmx4

DIOPT Version :9

Sequence 1:	NP_001287070.1	Gene:	Pdi / 39651	FlyBaseID:	FBgn0286818	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_083424.1	Gene:	Tmx4 / 52837	MGIID:	106558	Length:	335	Species:	Mus musculus

Alignment Length:	145	Identity:	41/145 - (28%)
Similarity:	66/145 - (45%)	Gaps:	16/145 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CALFLAASYVAASA-----EAEVKVEEG-VLVATVDNFKQLIADNEFVLVEFYAPWCGHCKALAP 64
            |...|.|:::||:|     :|.:..||. |...|..|: .|:.:.|::| :||||||..|:....
Mouse     6 CVPVLLAAWLAAAAAEGLEQAALPAEESRVQPMTASNW-TLVMEGEWML-KFYAPWCPSCQQTDS 68

  Fly    65 E---YAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADII 126
            |   :||..:.|     .|.:.|||...|..|:.::.|...|.....:.|....|.|.....|:.
Mouse    69 EWETFAKNGETL-----QISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIYEDLQ 128

  Fly   127 AWVTKKTGPPAKDLT 141
            .::.:|.....:.||
Mouse   129 NYILEKKWQSVEPLT 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_001287070.1	ER_PDI_fam	27..474	CDD:273457	33/119 (28%)
		pdi_dom	33..133	CDD:273454	28/102 (27%)
		PDI_b_family	137..231	CDD:239279	2/5 (40%)
		PDI_b'_family	244..347	CDD:239280
		PDI_a_PDI_a'_C	368..469	CDD:239293
Tmx4	NP_083424.1	Thioredoxin_like	33..133	CDD:294274	29/106 (27%)
Tmx4	NP_083424.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	222..316
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846784
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840