Protein Alignment Pdi and pdia8

DIOPT Version :10

• Sequence 1: NP_524079.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001003517.2
• Gene: pdia8 / 445123
• ZFINID: ZDB-GENE-040801-20
• Length: 493
• Species: Danio rerio
• Alignment Length: 490
• Identity: 154/490 - (31%)
• Similarity: 248/490 - (50%)
• Gaps: 46/490 - (9%)

  Fly     4 LICALFLAASYVAASAEAEVKVEEGVLVATVDNFKQLIADNEFVLVEFYAPWCGHCKALAPEYAK 68
            |:|.|       ..|..:..:....||..|..:|..|..::|.:||:||||||||||.||||:..
Zfish     9 LLCIL-------VCSLSSSAREHSDVLKLTDADFDYLAPEHETLLVKFYAPWCGHCKKLAPEFES 66

  Fly    69 AAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSG-SPVEYSGGRQAADIIAWVTKK 132
            ||.:|   :..:.|||||.|...|:.:.|.|.||||||.||:| ....|.|.|.|..|:.::.|:
Zfish    67 AASRL---KGTVTLAKVDCTANTEICKHYGVNGYPTLKIFRNGHESSSYDGPRSADGIVDYMKKQ 128

  Fly   133 TGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANAL-DSFVFGVSSNADVIAKY 196
            .||.:..|.|..|.|:|:...:.:::|.|...:|.:...|.|.|:.: :||.|..:::..:..||
Zfish   129 AGPDSVLLHSELDLEKFINHFDASVVGLFSGTDSSQLAEFLKGASLMRESFRFAHTTDLQLGQKY 193

  Fly   197 EAKDNGVVLFK------PFDDKKSVFEGELNEENLKKFAQVQSL---PLIVDFNHESASKIFGGS 252
            ......::||:      .|::......|.|:...|::|.:....   |.:...|.|...|
Zfish   194 GVTHESILLFRAPRLSSKFEESVVPHTGSLSVTGLRRFIRDNIFGLCPHMTKDNKEVLRK----- 253

  Fly   253 IKSHLLFFVSREGGHIEK----YVDPLKEIAKKYRDDILFVTISSDEEDHTRIFEFFGMNK---E 310
             :..|..:...:..|..|    :.:.:.::|.|:....:..::::..:....:.|.||::.   .
Zfish   254 -RDLLTAYYDLDYLHNPKGSNYWRNRVLKVATKFSSQGMLFSVANRNDFMEELEEEFGLSASDGN 317

  Fly   311 EVPTIRLIKLEEDMAKYK-PESDDLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVS 374
            |:|.:.:.....|  ||. .|......:::|:||:.:..|:||:::.|:.:|. .:...|||:|:
Zfish   318 ELPFVTIRTRTGD--KYSMREEFTRDGKSLESFLEDYFAGRLKRYVKSEPVPA-INNGVVKVVVA 379

  Fly   375 SNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELES-IKIS 438
            ..||.:..|..|.||:|||||||||||:|.|.|..|.|....:.:|||||||:|.|::.: ..:.
Zfish   380 DTFEEIVNDPEKDVLIEFYAPWCGHCKKLEPKYTALGEMLYSDPNIVIAKMDATVNDVPAGYDVQ 444

  Fly   439 SFPTIKYF----RKEDNKVIDFNLDRTLDDFVKFL 469
            .|||| ||    ||.:.|  .:...|.:.|||.||
Zfish   445 GFPTI-YFAAAGRKSEPK--RYEGAREVKDFVNFL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_524079.1	ER_PDI_fam	27..474	CDD:273457	150/467 (32%)
pdia8	NP_001003517.2	ER_PDI_fam	25..484	CDD:273457	150/467 (32%)