DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdi and tmx1

DIOPT Version :9

Sequence 1:	NP_001287070.1	Gene:	Pdi / 39651	FlyBaseID:	FBgn0286818	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001108605.1	Gene:	tmx1 / 323607	ZFINID:	ZDB-GENE-030131-2327	Length:	284	Species:	Danio rerio

Alignment Length:	148	Identity:	41/148 - (27%)
Similarity:	67/148 - (45%)	Gaps:	12/148 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CALFLAASYVAASAEAEVKVEEGVLVATVDNFKQLIADNEFVLVEFYAPWCGHCKALAP---EYA 67
            |.|.:.|:.|.|..||.   :.|.|....|...|.:...|: ::||:||||..|:.|.|   |:|
Zfish    17 CVLSILAACVVAQPEAP---KAGQLRVLTDGDWQEVLTGEW-MIEFFAPWCPACQQLEPVWTEFA 77

  Fly    68 KAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAWVTKK 132
            .....|.     :.:||||.|....|:.::.:...||:...:.|....|.|.|...|.::::.:|
Zfish    78 GWGDDLG-----VNIAKVDVTEHPGLSGRFIIMALPTIYHCKDGVFRRYQGDRSKEDFLSFIEEK 137

  Fly   133 TGPPAKDLTSVADAEQFL 150
            .....:.::|......||
Zfish   138 KWQSIEPVSSWFGPSSFL 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_001287070.1	ER_PDI_fam	27..474	CDD:273457	34/127 (27%)
		pdi_dom	33..133	CDD:273454	28/102 (27%)
		PDI_b_family	137..231	CDD:239279	3/14 (21%)
		PDI_b'_family	244..347	CDD:239280
		PDI_a_PDI_a'_C	368..469	CDD:239293
tmx1	NP_001108605.1	PDI_a_TMX	36..136	CDD:239292	30/105 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591993
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840