Protein Alignment Pdi and Pdilt

DIOPT Version :10

• Sequence 1: NP_524079.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_038963539.1
• Gene: Pdilt / 293544
• RGDID: 1307822
• Length: 615
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 144/524 - (27%)
• Similarity: 267/524 - (50%)
• Gaps: 36/524 - (6%)

  Fly     8 LFLAA--SYVAASAEAEVKV----------EEGVLVATVDNFKQLIADNEFVLVEFYAPWCGHCK 60
            |.|||  |.|..|.|.:..:          :..::|.|.....|.:.:..|::|.|:.|.....:
  Rat    34 LLLAACLSEVLGSPEMDTGINISQPLHILEDHNLMVLTPAGLTQTLNETRFLMVIFHNPTLKQSR 98

  Fly    61 ALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGS---PVEYSGGRQA 122
            .||.|..|||:...:.::.:...|||.|:|.||.:::.:...|.||.|..|:   |:......::
  Rat    99 KLAKELGKAAEIFGKGKNGLGFGKVDITMETELKQEFDITHAPELKLFYEGNRLEPISCKDVVES 163

  Fly   123 ADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDSFVFGVS 187
            ..::.|:.::....|....:..:...|:|...:.|:|||:|||.|.|:.|...........||..
  Rat   164 TALVVWLRRQISKKALLFNNSNEVADFVKSRPLVIVGFFQDLEEEVAELFYDTIKDFPELTFGAI 228

  Fly   188 SNADVIAKYEAKDNGVVLFKP--FDDKKSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFG 250
            ...:...::....:.|::||.  ...::.:.....|::.|.:..:.|....:::||.|:...|:.
  Rat   229 QIKNSFGRFHVILDSVLVFKKGRVVKRQELINDSTNKDYLNQVIKQQLTGFVIEFNPENKDLIYE 293

  Fly   251 GSIKSHLLFFVSREGGHIEKYVDPLKEIAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTI 315
            .:|.:|:|.|:|:........:...::|:|::::.||||.::|||..:.||||:|.:::..||::
  Rat   294 MNILNHMLLFISKNSEPYSTIIRHYRQISKEFQNKILFVLVNSDEPKNKRIFEYFQISRVNVPSV 358

  Fly   316 RLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESV 380
            :::.|..| |:||..:|:::.|:::.|...||....|:|..|:|:|:.||:.|||.||..||..|
  Rat   359 QILNLSSD-ARYKMPTDNITFESLKKFCNSFLSRTAKKHKSSEEIPKYWDQEPVKKLVGKNFNVV 422

  Fly   381 ALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELESIKISSFPTIKY 445
            ..||.|.|.|.|||||...|:.|.|:.::|..||:::..::|||:|.|||:::......:|..:.
  Rat   423 VFDKEKDVFVMFYAPWSEKCRVLLPLLEELGIKYQNHSTVIIAKIDITANDIQLANPEQYPFFRL 487

  Fly   446 FRKEDNKVIDFNLDRTLDDFVKFLDAN----------------GEVADSEPVEETEEE--EEAPK 492
            |..:..:.:.:..:.|:..|..||:::                .|||:.|.:.|.|.:  ::.|:
  Rat   488 FPTDSQEAVMYKGEHTMKGFCDFLESHVKVRIEEDDELLYIEQNEVAEEEVLAEPEMQHIDKLPE 552

  Fly   493 KDEL 496
            |..|
  Rat   553 KPPL 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_524079.1	ER_PDI_fam	27..474	CDD:273457	127/467 (27%)
Pdilt	XP_038963539.1	ER_PDI_fam	69..523	CDD:273457	127/454 (28%)