Protein Alignment Pdi and Pdia6

DIOPT Version :9

• Sequence 1: NP_001287070.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001004442.1
• Gene: Pdia6 / 286906
• RGDID: 628688
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 114/498 - (22%)
• Similarity: 167/498 - (33%)
• Gaps: 229/498 - (45%)

  Fly     6 CALFLAASYVAASAEAEVKVEEGVLVATVDNF-KQLIADNEFVLVEFYAPWCGHCKALAPEYAKA 69
            |..|||.|.:.:|:       :.|:..|..|| :::|..:...||||||||||||:.|.||:.||
  Rat    16 CTFFLAVSALYSSS-------DDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKA 73

  Fly    70 AQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFF--RSGSPVEYSGGRQAADIIAWVTKK 132
            |..|   :..:|:..|:|.....|..||.|:|:||:|.|  ....|.:|.|||
  Rat    74 ASAL---KDVVKVGAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGR------------ 123

  Fly   133 TGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDSFVFGVSSNADVIAKYE 197
            ||....| .:::...|.:||.
  Rat   124 TGEAIVD-AALSALRQLVKDR-------------------------------------------- 143

  Fly   198 AKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVS 262
                                                               .||
  Rat   144 ---------------------------------------------------LGG----------- 146

  Fly   263 REGGHIEKYVDPLKEIAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKY 327
            |.||:         ...|:.|.|      ||.::|                   :::|.:|
  Rat   147 RSGGY---------SSGKQGRGD------SSSKKD-------------------VVELTDD---- 173

  Fly   328 KPESDDLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVEF 392
                                               .:|||             .||.....:|||
  Rat   174 -----------------------------------TFDKN-------------VLDSEDVWMVEF 190

  Fly   393 YAPWCGHCKQLAPIYDQLAEKYKDNE--DIVIAKMDSTANELESIK--ISSFPTIKYFRKEDNKV 453
            |||||||||.|.|.:...|.:.|:..  .:.:|.:|:|.|::.:.:  |..|||||.|:|.::.|
  Rat   191 YAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIFQKGESPV 255

  Fly   454 IDFNLDRTLDDFV-KFLDANGEVADSEPVEETEE--EEEAPKK 493
             |::..||..|.| :.||.   .:|:.|..|..|  .|:..||
  Rat   256 -DYDGGRTRSDIVSRALDL---FSDNAPPPELLEIINEDIAKK 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_001287070.1	ER_PDI_fam	27..474	CDD:273457	101/454 (22%)
		pdi_dom	33..133	CDD:273454	40/102 (39%)
		PDI_b_family	137..231	CDD:239279	4/93 (4%)
		PDI_b'_family	244..347	CDD:239280	13/102 (13%)
		PDI_a_PDI_a'_C	368..469	CDD:239293	36/105 (34%)
Pdia6	NP_001004442.1	PDI_a_P5	31..133	CDD:239299	44/117 (38%)
		PDI_a_P5	166..271	CDD:239299	42/176 (24%)
		P5_C	280..409	CDD:239281	5/15 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910