Protein Alignment Pdi and mpd1

DIOPT Version :10

• Sequence 1: NP_524079.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_593653.1
• Gene: mpd1 / 2542841
• PomBaseID: SPAC13F5.05
• Length: 363
• Species: Schizosaccharomyces pombe
• Alignment Length: 355
• Identity: 87/355 - (24%)
• Similarity: 145/355 - (40%)
• Gaps: 64/355 - (18%)

  Fly    36 NFKQLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVR 100
            ||::.:......||.|||||||:||.|.|.|.|.|..| ....|:.....||.....:..||.|:
pombe    40 NFRKFVKAKGPSLVVFYAPWCGYCKKLVPTYQKLASNL-HSLLPVTAVDCDADQNRAVCSQYQVQ 103

  Fly   101 GYPTLKFF------RSGSPVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKD--NEIAI 157
            |:||:|..      .|.|..:|:|.|....:..:|:.......|.|||.|..::|::|  |...:
pombe   104 GFPTIKLVYPSSKGSSLSSTDYNGDRSYKSLQKFVSDSIPSKVKILTSEAKTQKFIQDAQNSSKV 168

  Fly   158 IGFFKDLESEEAK---TFTKVANALDSFVF-------GVSSNADVIAKYEAKDNGVVLFKPFDDK 212
            |     |.|::.|   .:..::|...|..|       .|:...::.|..:..|..::..|..::.
pombe   169 I-----LISQKMKPTLLYKSLSNEFSSLPFSFMPAKANVNDLFNISAYVDTSDLPILFIKHPNNG 228

  Fly   213 KSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGGHI-------EK 270
            .|.|...||.:::.:|.|               |.|...:...:|..|.|::...|       :.
pombe   229 TSFFSNSLNRDSIVEFLQ---------------SSIKDNNFSEYLATFCSKKSCIITIQDKDSDS 278

  Fly   271 YVDPLKEIAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKY-KPESDDL 334
            .:|  :.|.||| ..:.||.:..:.....|:.:...:...:...:.|.|...:...| ||
pombe   279 GID--ESIRKKY-PKLHFVRLGRNTTVAERLEDTLDLGYSDTFLLSLKKSHYNAKPYGKP----- 335

  Fly   335 SAETIEAFLKKFL-DGKLKQHLLSQELPED 363
                    |:::| |.:::|...|..||.|
pombe   336 --------LRRWLEDIQVQQAGPSVSLPND 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_524079.1	ER_PDI_fam	27..474	CDD:273457	87/355 (25%)
mpd1	NP_593653.1	ER_PDI_fam	31..>257	CDD:273457	62/237 (26%)
		PDI_a_MPD1_like	32..139	CDD:239300	34/99 (34%)