DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdi and SPAC13F5.05

DIOPT Version :9

Sequence 1:	NP_001287070.1	Gene:	Pdi / 39651	FlyBaseID:	FBgn0286818	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_593653.1	Gene:	SPAC13F5.05 / 2542841	PomBaseID:	SPAC13F5.05	Length:	363	Species:	Schizosaccharomyces pombe

Alignment Length:	355	Identity:	87/355 - (24%)
Similarity:	145/355 - (40%)	Gaps:	64/355 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 NFKQLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVR 100
            ||::.:......||.|||||||:||.|.|.|.|.|..| ....|:.....||.....:..||.|:
pombe    40 NFRKFVKAKGPSLVVFYAPWCGYCKKLVPTYQKLASNL-HSLLPVTAVDCDADQNRAVCSQYQVQ 103

  Fly   101 GYPTLKFF------RSGSPVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKD--NEIAI 157
            |:||:|..      .|.|..:|:|.|....:..:|:.......|.|||.|..::|::|  |...:
pombe   104 GFPTIKLVYPSSKGSSLSSTDYNGDRSYKSLQKFVSDSIPSKVKILTSEAKTQKFIQDAQNSSKV 168

  Fly   158 IGFFKDLESEEAK---TFTKVANALDSFVF-------GVSSNADVIAKYEAKDNGVVLFKPFDDK 212
            |     |.|::.|   .:..::|...|..|       .|:...::.|..:..|..::..|..::.
pombe   169 I-----LISQKMKPTLLYKSLSNEFSSLPFSFMPAKANVNDLFNISAYVDTSDLPILFIKHPNNG 228

  Fly   213 KSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGGHI-------EK 270
            .|.|...||.:::.:|.|               |.|...:...:|..|.|::...|       :.
pombe   229 TSFFSNSLNRDSIVEFLQ---------------SSIKDNNFSEYLATFCSKKSCIITIQDKDSDS 278

  Fly   271 YVDPLKEIAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKY-KPESDDL 334
            .:|  :.|.||| ..:.||.:..:.....|:.:...:...:...:.|.|...:...| ||
pombe   279 GID--ESIRKKY-PKLHFVRLGRNTTVAERLEDTLDLGYSDTFLLSLKKSHYNAKPYGKP----- 335

  Fly   335 SAETIEAFLKKFL-DGKLKQHLLSQELPED 363
                    |:::| |.:::|...|..||.|
pombe   336 --------LRRWLEDIQVQQAGPSVSLPND 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_001287070.1	ER_PDI_fam	27..474	CDD:273457	87/355 (25%)
		pdi_dom	33..133	CDD:273454	35/102 (34%)
		PDI_b_family	137..231	CDD:239279	24/105 (23%)
		PDI_b'_family	244..347	CDD:239280	20/110 (18%)
		PDI_a_PDI_a'_C	368..469	CDD:239293
SPAC13F5.05	NP_593653.1	PDI_a_MPD1_like	32..139	CDD:239300	34/99 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910