Protein Alignment Pdi and erp-44.3

DIOPT Version :9

• Sequence 1: NP_001287070.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_501357.3
• Gene: erp-44.3 / 185676
• WormBaseID: WBGene00018358
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 99/495 - (20%)
• Similarity: 168/495 - (33%)
• Gaps: 169/495 - (34%)

  Fly    33 TVDNFKQLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKL--AKVDATVEGELAE 95
            |..|..::|.::....|.|.|.||...:.|...:::||.....|....|.  ..||...|..|..
 Worm    51 TSTNHDEIIQNSRLTFVAFTASWCPFSRKLMSSFSQAAADYQAKYPDRKTVWGNVDCMAEDYLMN 115

  Fly    96 QYAVRGYPTLK-FFRSGSPVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEIAIIG 159
            :|::..:||:| ||......||.|.||...:|.::.|                   .:|..:::.
 Worm   116 KYSITKFPTMKVFFYGYMMTEYRGSRQVKGLIEYIEK-------------------MENTSSLVN 161

  Fly   160 FFKDLESEEAKTFTKVANALDSFVFGVSSNADVIAKYEAKDNGVVLF------KPFDDKKSVFEG 218
            .      .||::.|:..|                  |.....|.::.      .||
 Worm   162 L------NEAESLTQWQN------------------YVIPQKGTLILWFPRGSPPF--------- 193

  Fly   219 ELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGGHIEKY---VDPLKEIA- 279
               |..||..|.:.|..::|....|:..|     .:.|.|:| |.:|.|:|::   |...|||.
 Worm   194 ---ELILKAIALIHSQLVVVVPISENLLK-----HEDHQLWF-SLDGEHVERFEGSVSNFKEIVE 249

  Fly   280 ---KKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKYK----PESDDLSAE 337
               ||....:..:|..:.||          |.::..|.:.|::.::|:...|    ....:|..:
 Worm   250 WIKKKSAGMVRELTFENMEE----------MVEDGKPLLILLRKKDDIETEKQFVTTIRRELDQD 304

  Fly   338 TIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVE-----FYAPWC 397
            |:........|||                  |...|..:|.. .||....:|::     |.:||.
 Worm   305 TLLKLAPVMADGK------------------VLTAVLRHFNK-GLDDLPFLLIDQFTHSFPSPWK 350

  Fly   398 -------GHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELESIKISSFPTIKYFRKEDNKVID 455
                   |:.||.      :|:.:.||                           :.||
 Worm   351 GNEIFAEGNIKQF------VADLFNDN---------------------------HHRK------- 375

  Fly   456 FNLDRTLDDFVKFLDANGEVADSEPVEETEEEEEAPKKDE 495
              |...|::.::.:     |.::|.:|:...||:..|..|
 Worm   376 --LHEKLNELIQKI-----VTETEEIEKQASEEKVEKPTE 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_001287070.1	ER_PDI_fam	27..474	CDD:273457	92/472 (19%)
		pdi_dom	33..133	CDD:273454	30/102 (29%)
		PDI_b_family	137..231	CDD:239279	13/99 (13%)
		PDI_b'_family	244..347	CDD:239280	24/113 (21%)
		PDI_a_PDI_a'_C	368..469	CDD:239293	19/112 (17%)
erp-44.3	NP_501357.3	Thioredoxin_like	45..150	CDD:381987	29/98 (30%)
		Thioredoxin_like	259..369	CDD:381987	26/144 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910