Protein Alignment Pdi and pdi-6

DIOPT Version :9

• Sequence 1: NP_001287070.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_509190.1
• Gene: pdi-6 / 180974
• WormBaseID: WBGene00015168
• Length: 440
• Species: Caenorhabditis elegans
• Alignment Length: 500
• Identity: 110/500 - (22%)
• Similarity: 161/500 - (32%)
• Gaps: 220/500 - (44%)

  Fly    10 LAASYVAASAEAEVKVEEGVLVATVDNFK-QLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQL 73
            |.||....|.......::.|:..|..||: ::|..::..:||||||||||||:|.|||.|||..|
 Worm     7 LLASLAITSVCGMYSKKDDVVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAASAL 71

  Fly    74 AEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSG--SPVEYSGGRQAADIIAWVTKKTGPP 136
               :...|:..||.|....:...|.|:|:||||.|.:.  .|.:|:|.|.|
 Worm    72 ---KGVAKVGAVDMTQHQSVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTA-------------- 119

  Fly   137 AKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDSFVFGVSSNADVIAKYEAKDN 201
                       |.:.|:.:|        |:::|                      |.|:...|.:
 Worm   120 -----------QAIADSVLA--------EAKKA----------------------VSARLGGKSS 143

  Fly   202 GVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGG 266
            |                                        .|:|....||.|        |.||
 Worm   144 G----------------------------------------SSSSGSGSGSGK--------RGGG 160

  Fly   267 HIEKYVDPLKEIAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKYKPES 331
                                                   |...|.|.
 Worm   161 ---------------------------------------GSGNEVVE------------------ 168

  Fly   332 DDLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPW 396
                                                    |..:|||.:.|:.....||||:|||
 Worm   169 ----------------------------------------LTDANFEDLVLNSKDIWLVEFFAPW 193

  Fly   397 CGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELESIK--ISSFPTIKYFR--KEDNKVIDFN 457
            |||||.|.|.:...|.:.|..  :.:..:|:|.:.:.:.|  |..|||||||.  .:.:...|::
 Worm   194 CGHCKSLEPQWKAAASELKGK--VRLGALDATVHTVVANKFAIRGFPTIKYFAPGSDVSDAQDYD 256

  Fly   458 LDRTLDDFVKFLDANGEVADSEPVEETEE------EEEAPKKDEL 496
            ..|...|.|.:..|..:  ::.|..|..|      .|:|.|:.:|
 Worm   257 GGRQSSDIVAWASARAQ--ENMPAPEVFEGINQQVVEDACKEKQL 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_001287070.1	ER_PDI_fam	27..474	CDD:273457	99/453 (22%)
		pdi_dom	33..133	CDD:273454	41/102 (40%)
		PDI_b_family	137..231	CDD:239279	9/93 (10%)
		PDI_b'_family	244..347	CDD:239280	11/102 (11%)
		PDI_a_PDI_a'_C	368..469	CDD:239293	36/104 (35%)
pdi-6	NP_509190.1	PDI_a_P5	25..127	CDD:239299	44/129 (34%)
		PDI_a_P5	165..269	CDD:239299	38/163 (23%)
		P5_C	278..407	CDD:239281	5/21 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910