Protein Alignment Pdi and Y49E10.4

DIOPT Version :10

• Sequence 1: NP_524079.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_499613.1
• Gene: Y49E10.4 / 176664
• WormBaseID: WBGene00013030
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 490
• Identity: 95/490 - (19%)
• Similarity: 154/490 - (31%)
• Gaps: 229/490 - (46%)

  Fly     7 ALFLAASYVAASAEAEVKVEEGVLVATVDNF-KQLIADNEFVLVEFYAPWCGHCKALAPEYAKAA 70
            :|::...:..:.:......::.|...|..|| .:::..:...:||||||:|||||:|.|||.|||
 Worm     4 SLWILLVFAISGSSTFYTAKDSVFELTDSNFDAKVLKSDRIWIVEFYAPYCGHCKSLVPEYKKAA 68

  Fly    71 QQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFF---RSGSPVEYSGGRQAADIIAWVTKK 132
            :.|   :...::..:||||..::..:|:::||||:|.|   ....|::|:|.|.|..|
 Worm    69 KLL---KGIAEIGAIDATVHQKIPLKYSIKGYPTIKIFGATEKSKPIDYNGPRTAKGI------- 123

  Fly   133 TGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDSFVFGVSSNADVIAKYE 197
                                                                     ||.:.|
 Worm   124 ---------------------------------------------------------ADAVKK-- 129

  Fly   198 AKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVS 262
                                                                             
 Worm   130 ----------------------------------------------------------------- 129

  Fly   263 REGGHIEKYVDPLKEIAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKY 327
                                                                             
 Worm   130 ----------------------------------------------------------------- 129

  Fly   328 KPESDDLSAETIEAFLKKFLDGKLKQHLLSQELPEDWD-KNPVKVLVSSNFESVALDKSKSVLVE 391
                      :||..|::.|.||      |.|..:..| |..|.||..|||:.:.|:..:..:||
 Worm   130 ----------SIEKSLEQRLKGK------SSEKSKKSDKKGKVVVLTDSNFDKLVLNSKEPWMVE 178

  Fly   392 FYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANE--LESIKISSFPTIKYF---RKEDN 451
            |:|||||||::|.|.:.:.||:....  :....:|:||:|  .:...|..|||||:|   ....:
 Worm   179 FFAPWCGHCQKLEPEWKKAAEEMGGR--VKFGALDATAHESIAQKFGIRGFPTIKFFAPGTSSAS 241

  Fly   452 KVIDFNLDRTLDDFVKFLDANGE--VADSEPVEET 484
            ...|:...||..|.:.:.::..:  .|..|.||.|
 Worm   242 DAEDYQGGRTSTDLISYAESKYDDFGAAPEVVEGT 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_524079.1	ER_PDI_fam	27..474	CDD:273457	89/456 (20%)
Y49E10.4	NP_499613.1	PDI_a_P5	26..127	CDD:239299	42/167 (25%)
		PDI_a_P5	156..259	CDD:239299	36/104 (35%)
		P5_C	269..405	CDD:239281	4/8 (50%)