Protein Alignment Pdi and Txndc5

DIOPT Version :9

• Sequence 1: NP_001287070.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001258259.1
• Gene: Txndc5 / 100362805
• RGDID: 2323973
• Length: 417
• Species: Rattus norvegicus
• Alignment Length: 501
• Identity: 120/501 - (23%)
• Similarity: 192/501 - (38%)
• Gaps: 144/501 - (28%)

  Fly     4 LICALFLAASYVAASAEAEVKVEEGV-------LVATVDNFKQLI-ADNEFVLVEFYAPWCGHCK 60
            |...|.|..:...|.|: ||:.:.||       .:.|.|.|...| :...||:  |:|||||||:
  Rat    18 LATLLLLLGARKGARAQ-EVEADSGVEQDPHAKHLYTADMFTHGIQSAAHFVM--FFAPWCGHCQ 79

  Fly    61 ALAPEYAKAAQQLAEK-----ESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSG-SPVEYSGG 119
            .|.|.:    ..|.:|     ::.:.:||||.|...::.....||||||||||:.| ..|:|.|.
  Rat    80 RLQPTW----NDLGDKYNSMEDAKVYVAKVDCTANSDVCSAQGVRGYPTLKFFKPGQEAVKYQGP 140

  Fly   120 RQAADIIAWVTK------KTGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTK---- 174
            |....:..|:.:      .|..|..:.....:.:|.|  .|::...|  :|...:...|.|
  Rat   141 RDFETLENWMLQTLNEEPATPEPEAEPPRAPELKQGL--YELSANNF--ELHVSQGNHFIKFFAP 201

  Fly   175 -------VANALDSFVFGVSSNADV-IAKYEAKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQV 231
                   :|...:....|:..:..| |.|.:...:..|..:                     .||
  Rat   202 WCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYAVCSE---------------------HQV 245

  Fly   232 QSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGGHIEKYVDPLKEIAKKYRDDILFVTISSDEE 296
            :..|.                    ||:|  |:|..:::|
  Rat   246 RGYPT--------------------LLWF--RDGKKVDQY------------------------- 263

  Fly   297 DHTRIFEFFGMNKEEVPTIRLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDGKLKQHLLSQELP 361
                      ..|.::.::|      |..:.:.:..:.:.||:|         ..:..:|:.|.|
  Rat   264 ----------KGKRDLESLR------DYVQSQLQGSEAAPETVE---------PSEAPVLAAEPP 303

  Fly   362 EDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEK-YKDNEDIVIAKM 425
              .||..|..|...:||...  ......|:||||||||||.|||.:::|::| :....|:.||::
  Rat   304 --GDKGTVLALTEKSFEDTI--AQGITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLADVTIAEV 364

  Fly   426 DSTANE--LESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFL 469
            |.||..  .....:..:||:..||..: ||.:.|..|.||....|:
  Rat   365 DCTAERGVCSKYSVRGYPTLLLFRGGE-KVGEHNGGRDLDSLHSFV 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_001287070.1	ER_PDI_fam	27..474	CDD:273457	113/478 (24%)
		pdi_dom	33..133	CDD:273454	39/112 (35%)
		PDI_b_family	137..231	CDD:239279	13/105 (12%)
		PDI_b'_family	244..347	CDD:239280	12/102 (12%)
		PDI_a_PDI_a'_C	368..469	CDD:239293	36/103 (35%)
Txndc5	NP_001258259.1	PDI_a_ERp46	47..150	CDD:239303	38/108 (35%)
		ER_PDI_fam	52..417	CDD:273457	111/466 (24%)
		PDI_a_ERp46	176..276	CDD:239303	24/187 (13%)
		PDI_a_ERp46	308..409	CDD:239303	36/103 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910