Protein Alignment Cep135 and tag-278

DIOPT Version :9

• Sequence 1: NP_001189108.1
• Gene: Cep135 / 39647
• FlyBaseID: FBgn0036480
• Length: 1065
• Species: Drosophila melanogaster
• Sequence 2: NP_508635.2
• Gene: tag-278 / 180658
• WormBaseID: WBGene00015356
• Length: 1163
• Species: Caenorhabditis elegans
• Alignment Length: 972
• Identity: 199/972 - (20%)
• Similarity: 406/972 - (41%)
• Gaps: 191/972 - (19%)

  Fly   216 LTAAGEQLEFFKRKVEARNREIRRLNDMLAGGR--PLAALAKDCCYKDVGALSQ----------- 267
            :.|..|::...|:..|||.:..:.|.|.....:  .|..|.|: ..|::..|.|
 Worm   207 IIALSEEVLGAKKDFEARMKSFQALQDKFEREKEQALEKLRKE-HQKEIQVLEQRFSDTQLLNLE 270

  Fly   268 -----DIDLLQREKSDLMMQVREFQDKMHDAMQRALSSEED-----KIKLQTQLEELKEAALQVE 322
                 :|..|:.|:..|..:.....:.....::||.|..|.     |:....:||.|::....::
 Worm   271 QKYIIEIQRLEEERKSLRTEKERLGETFEMKLRRAQSLYETELTAAKMLYTKELEALRDHEEALK 335

  Fly   323 QQANAEIDAKESELRQLQLELKKKGKDHRLTGGFASNQSD-------KHNLNERLNLLTRREEEL 380
            ::..|..|.....|::|||:.|:..:|      ..|.::|       .||..:.:..||:..:::
 Worm   336 EELLARQDEFHDRLQELQLQSKRSRED------LVSCKNDVTALEKKLHNKEKEVQTLTKELDQV 394

  Fly   381 QA-TNEK-------------HKKKIQKMQ------AKILELQKELKDQNKHSNVTLDEEKIRLSS 425
            :. ||:|             ::||.|:.:      |::|.:.:..|::.:.....|..|...|.:
 Worm   395 KTETNDKIRRLTEVTSEFAEYRKKFQQQEEELRRKARLLTVVEAAKEKLESVISDLQVEVKALKN 459

  Fly   426 ERDFFQKEYLRLMSKTGSESEI---------AFLHAQIKSKDEELKALRSELFHGGKQQFSPQKS 481
            :.:|.:||...|.|::.|::::         |.||:..|.|:...:.....|....:|..|.:.:
 Worm   460 KVEFLEKERENLQSQSESQTQLQSSQVDALEAVLHSVTKEKETTKEHYEGLLLKERQQAESREHA 524

  Fly   482 VQYETLPPPTASSITSTVTSNTSDCVQAAIARVERERDCARTELER-VRCERDTLREKQLSTVQL 545
            ::.|                     ....:..:|.:....:.|||. .|.::|.|||
 Worm   525 MKKE---------------------FSCKLNELEEQYTSLKEELEESARLDKDELRE-------- 560

  Fly   546 HADELQALRLRNEE---------LNDRLRQMERDNRELNSARLPTETNLVLLKEDLLQMRQRVAS 601
             |.|::...||.|:         |..::...|:|:.....|::..:|:  .|...|.:.|:|:..
 Worm   561 -ASEIEIQALRTEKSILAAEIRVLTQKIEDEEQDDITEQLAKIVEDTS--QLTRTLEEYRERITG 622

  Fly   602 MQTEIDQLKTE-NDQITMLNDQNERIIADYQSKLLVAERQRQSADVRA---------STLDSSRE 656
            ...||..|:.: ..:|:...|:| |::.:...|.|.|.::..:..||.         |..::.:|
 Worm   623 KDAEILNLRKQLEKEISHTEDRN-RLLHENTQKELEAHKETHTETVRVLEAEIDQFKSAFENEQE 686

  Fly   657 SNRSEVTQLRMDLGALRQTYIS----LEH----------EKDTLLHQLDTKTERVYKLEYELKDC 707
            ..:.:..::| :|.|..:|.:|    ::|          :||.||.:|::|.:.:..|:.|:...
 Worm   687 YGKEKSAKIR-ELEAQNKTLLSEMEKVKHVAENLEAFTSDKDNLLEELESKNKNIEHLKQEIAQL 750

  Fly   708 KEKRNALE-QNVKDLEDQLRKLANRNRQRDSELTETSTESKTLRQQIVALKASRDEAIAENRRLM 771
            .||.:..| :...:||..:.:|...|..:..::.:.......:..|:..:|   ||.:.:|..:
 Worm   751 NEKISTKETEKDSELEKTIAQLEIDNSSKSDQIEKLHLRVNDMLDQMGTIK---DELVKKNEEI- 811

  Fly   772 DKLSDAQVEARTLQKKLTDSELQVANMKQQLHKYVQEVKKAEDLLIQKVSSKFKEKERDDMLDQY 836
             |...|:. |:.|:....:||.::|::.::..|   |::..:..:.:|.:....:.||.:.|:.
 Worm   812 -KTISAKT-AQLLESNTVESETKLASVTEEREK---EIQSFQTQISEKDNEVLTKAERINELET- 870

  Fly   837 HCLTQGQATLEGNNQSLECEAVEFRRQICELECEV---HSLKEQLQLRQCALHDMEVQLTAARAS 898
             ||.:.:..|.|....|:    :..:|:.|....|   :|::|::..::..:::|..:|
 Worm   871 -CLKEREVELTGMRTKLD----DMTQQLNEETTVVLFDNSIQEKIDEKEATINEMNERL------ 924

  Fly   899 VRCLERELENARDDIRVQKVDLEARKELCDKL--------------DVERSKLNAELNDVNEIRK 949
             :..|.|:....:::.:||...|.|.|...||              ..|:|.:.||:..|.:..|
 Worm   925 -KSRENEIAKLHEEMYMQKTQNEKRNEEQSKLFQELMFEKEQLEAEKAEQSHIEAEVEQVFQADK 988

  Fly   950 --KLEKQCEKLRDELQ-QSLAINQVTNETTDLMLGRLHNDQQHQEDDDIRSKHEMDRLQRQLQQT 1011
              |.::|.|.|.:.|| ::..|.|:.:..||......|..::.    .|.|.........|::..
 Worm   989 ESKWKEQIEDLENALQRKNELIQQLQDRQTDESTSEPHTKKRM----SITSHGVFQNFVSQMKDK 1049

  Fly  1012 LDQLQEERVRC---RHHEELAEKWEQQVRDLRRNLADDRYNQARTREVS------PRVPSKT 1064
            .::..|:|.|.   :..|:..||.|:..::..:.||.:: :.||.:..|      .|.|:|:
 Worm  1050 REEASEKRTRKEAEKKAEKEKEKAEKAAKEAAKELAREK-SPARAKSPSILTRLRDRSPAKS 1110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cep135	NP_001189108.1	Smc	<203..963	CDD:224117	174/859 (20%)
		DUF342	<302..421	CDD:302792	30/150 (20%)
tag-278	NP_508635.2	SMC_prok_B	191..1016	CDD:274008	178/871 (20%)
		DUF342	<205..299	CDD:302792	18/92 (20%)
		SPFH_like	<531..726	CDD:302763	43/207 (21%)
		Bacillus_HBL	<695..755	CDD:283454	16/60 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I3372
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050