Protein Alignment CG13458 and MSS51

DIOPT Version :10

• Sequence 1: NP_648748.1
• Gene: CG13458 / 39646
• FlyBaseID: FBgn0036479
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001019764.1
• Gene: MSS51 / 118490
• HGNCID: 21000
• Length: 460
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 114/570 - (20%)
• Similarity: 174/570 - (30%)
• Gaps: 197/570 - (34%)

  Fly   122 PKEIKSEEKKPKIS--------STSVTPKLKTEAKASG-------ISKEEEINDLLKCLGSKLPK 171
            |:..:...|||..|        :|.|||...|.:|...       .|.::.:..|.:.:..||..
Human     3 PRSRRRRHKKPPSSVAPIIMAPTTIVTPVPLTPSKPGPSIDTLGFFSLDDNVPGLSQLILQKLNM 67

  Fly   172 GS---------GESPAAALFSNLGKLFSQAPPSDVESSDEEVEEYVEYIYKPRQYFMASLCNFCK 227
            .|         |.:|.:.        |....|.::....|:...:               |..|:
Human    68 KSYEEYKLVVDGGTPVSG--------FGFRCPQEMFQRMEDTFRF---------------CAHCR 109

  Fly   228 SDLCG--QNRI--PCSRCGLSYYCSSGHMKDD-QEHRQLCYALR-QTVDRNGHEMFYKCGDFS-- 284
            :...|  .:::  .|.||...|||.....|.| ..||::|..|| ..|||. .|.....|||.
Human   110 ALPSGLSDSKVLRHCKRCRNVYYCGPECQKSDWPAHRRVCQELRLVAVDRL-MEWLLVTGDFVLP 173

  Fly   285 --------------DEQFRSFRIVCIRQVEKEMNRQLSATERELLLFPLICADSKCREHRFKRLS 335
                          |..|            ......|.||           .|:....|....|
Human   174 SGPWPWPPEAVQDWDSWF------------SMKGLHLDAT-----------LDAVLVSHAVTTL- 214

  Fly   336 MCGGCGEVAFCKDKPEHRGKEHAKWCGAYQIFKAFIMFQEQFGRMEPSLPSKILRELPMACSNTK 400
                                    |...              ||..|. |..:           :
Human   215 ------------------------WASV--------------GRPRPD-PDVL-----------Q 229

  Fly   401 QMMKKLSFNVTNECEYAALTQVSTGPLTAWFALK-LCERLRNCEEMTLHLIGAEIEFEADMLQKW 464
            ..:|:|            ||.|.:.|||....|: |...:|.....|:|::||         ...
Human   230 GSLKRL------------LTDVLSRPLTLGLGLRALGIDVRRTGGSTVHVVGA---------SHV 273

  Fly   465 ELFLL---------HITPAVKTLNVVFVGPELNPNNISFEQLKKIKCCRFCRKAQRTVNYHFENS 520
            |.||.         ::.|....|.||.||.::   ...|.|........     ..|:.......
Human   274 ETFLTRPGDYDELGYMFPGHLGLRVVMVGVDV---ATGFSQSTSTSPLE-----PGTIQLSAHRG 330

  Fly   521 LYHDYCRE------SHFLQPNLICFFNCGLYRSTGFALEDTWPDTIQAALNLNCPIVVTSYTKYE 579
            ||||:..|      :|  .|:|:..|:.|.:.|..  |.:.|..|:....:...|.::|.|:..|
Human   331 LYHDFWEEQVETGQTH--HPDLVAAFHPGFHSSPD--LMEAWLPTLLLLRDYKIPTLITVYSHQE 391

  Fly   580 APLDMIQFINQSNRHLNVVMPPTVNPFSSEKPERNFISDNEASFMFKNFY 629
            . :..:|.:.:.:.|:...   ..|||.|.|||:.:.|.|:.......:|
Human   392 L-VSSLQILVELDTHITAF---GSNPFMSLKPEQVYSSPNKQPVYCSAYY 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13458	NP_648748.1	zf-Mss51	223..276	CDD:433505	19/58 (33%)
		MSS51_C	426..615	CDD:466330	49/204 (24%)
MSS51	NP_001019764.1	zf-MYND	105..149	CDD:460312	13/43 (30%)
		MSS51_C	243..423	CDD:466330	49/204 (24%)