DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CTPsyn and AT1G30820

DIOPT Version :9

Sequence 1:	NP_001287067.1	Gene:	CTPsyn / 39645	FlyBaseID:	FBgn0266452	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_174368.1	Gene:	AT1G30820 / 839964	AraportID:	AT1G30820	Length:	600	Species:	Arabidopsis thaliana

Alignment Length:	627	Identity:	334/627 - (53%)
Similarity:	415/627 - (66%)	Gaps:	37/627 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKYILVTGGVISGVGKGVIASSFGTLLKSCGLDVTSIKIDPYINIDAGTFSPYEHGEVYVLDDGA 65
            |||:||||||:||:||||.|||.|.|||:|||.|||||||||:|.||||.||:|||||:|||||.
plant     1 MKYVLVTGGVVSGLGKGVTASSIGVLLKACGLRVTSIKIDPYLNTDAGTMSPFEHGEVFVLDDGG 65

  Fly    66 EVDLDLGNYERFLDVTLHRDNNITTGKIYKLVIEKERTGEYLGKTVQVVPHITDAIQEWVERVAQ 130
            ||||||||||||||:.|.|||||||||||:.||.|||.|:|||||||||||:|||||:|:||||.
plant    66 EVDLDLGNYERFLDIKLTRDNNITTGKIYQHVIAKERKGDYLGKTVQVVPHVTDAIQDWIERVAV 130

  Fly   131 TPVQGSSKP-QVCIVELGGTIGDIEGMPFVEAFRQFQFRVKRENFCLAHVSLVPLPKATGEPKTK 194
            .||.|...| .||::||||||||||..||:||..||.:||...||||.||||||:....||.|||
plant   131 IPVDGEEDPADVCVIELGGTIGDIESAPFIEALGQFSYRVGPGNFCLVHVSLVPVLNVVGEQKTK 195

  Fly   195 PTQSSVRELRGCGLSPDLIVCRSEKPIGLEVKEKISNFCHVGPDQVICIHDLNSIYHVPLLMEQN 259
            |||.||:.|||.||:||::.|||.||:...||||::.||||..:.:..::|:.:|:.:|||::..
plant   196 PTQHSVKGLRGLGLTPDILACRSTKPLEDNVKEKLAQFCHVPLEYIFTLYDVPNIWRIPLLLKDQ 260

  Fly   260 GVIEYLNERLQLNIDMSKRTKCLQQWRDLARRTETVRREVCIAVVGKYTKFTDSYASVVKALQHA 324
            ..  :|.....||:........|.:|...|...:.:...|.||||||||..:|:|.||:|||.||
plant   261 KA--HLAISKVLNLASILNEPSLGEWTSRAELCDNLHVPVRIAVVGKYTGLSDAYLSVLKALLHA 323

  Fly   325 ALAVNRKLELVFIESCLLEEETLHSEPSKYHKEWQKLCDSHGILVPGGFGSRGMEGKIRACQWAR 389
            ::|..:||.:.::.:|.||:||....|..|...|:.|....|||||||||.||:||||.|.::||
plant   324 SVACRKKLVVDWVPACDLEKETEKENPDAYKAAWKLLKGVDGILVPGGFGDRGVEGKILAAKYAR 388

  Fly   390 ENQKPLLGICLGLQAAVIEFARNKLGLKDANTTEIDPNTANALVIDMPEHHTGQLGGTMRLGKRI 454
            ||:.|.||||||:|.|||||||:.|.|:|||:||.:|.|.:..:|.|||.....:|||||||.|.
plant   389 ENKIPFLGICLGMQIAVIEFARSVLSLQDANSTEFNPETKHPCIIFMPEGSKTHMGGTMRLGSRK 453

  Fly   455 TVFSDGPSVIRQLYGNPKSVQERHRHRYEVNPKYVHLLEEQGMRFVGTDVDKTRMEIIELSGHPY 519
            ::|:...|...:||.|...|.|||||||||||..|..||:.|:.|...|....|||||||..||:
plant   454 SIFNVKDSKSAKLYENKSFVDERHRHRYEVNPDMVERLEKAGLSFAAKDETGKRMEIIELPNHPF 518

  Fly   520 FVATQYHPEYLSRPLKPSPPFLGLILASVDRLNQYIQRGCRLSPRQLSDASSDEEDSVVGLAGAT 584
            |:..|:|||:.|||.|.||.|||||.||...|                       |:|:..|.|.
plant   519 FIGAQFHPEFKSRPGKASPLFLGLIAASCGEL-----------------------DTVLNPASAH 560

  Fly   585 K-SLSSLKIPITPT----NGIS-KSCNGSISTSDSEGACGGV 620
            : |:|:     .||    ||.| ||.||......:.|.|.|:
plant   561 QHSISN-----GPTNIFINGTSKKSPNGLADVRYNNGYCNGL 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CTPsyn	NP_001287067.1	PLN02327	1..556	CDD:215186	316/555 (57%)
		CTP_synth_N	2..271	CDD:283956	173/269 (64%)
		GATase1_CTP_Synthase	299..544	CDD:153217	132/244 (54%)
AT1G30820	NP_174368.1	PLN02327	1..557	CDD:215186	318/580 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	368	1.000	Domainoid score	I181
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	638	1.000	Inparanoid score	I187
OMA	1	1.010	-	-		QHG60688
OrthoDB	1	1.010	-	-		D810128at2759
OrthoFinder	1	1.000	-	-		FOG0001109
OrthoInspector	1	1.000	-	-		otm2421
orthoMCL	1	0.900	-	-		OOG6_100470
Panther	1	1.100	-	-	LDO	PTHR11550
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X676
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980