DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CTPsyn and emb2742

DIOPT Version :9

Sequence 1:	NP_001287067.1	Gene:	CTPsyn / 39645	FlyBaseID:	FBgn0266452	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_187873.1	Gene:	emb2742 / 820447	AraportID:	AT3G12670	Length:	591	Species:	Arabidopsis thaliana

Alignment Length:	609	Identity:	328/609 - (53%)
Similarity:	412/609 - (67%)	Gaps:	40/609 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKYILVTGGVISGVGKGVIASSFGTLLKSCGLDVTSIKIDPYINIDAGTFSPYEHGEVYVLDDGA 65
            |||:||||||:||:||||.|||.|.||::|||.|||||||||:|.||||.||:|||||:|||||.
plant     1 MKYVLVTGGVVSGLGKGVTASSIGLLLQACGLRVTSIKIDPYLNTDAGTMSPFEHGEVFVLDDGG 65

  Fly    66 EVDLDLGNYERFLDVTLHRDNNITTGKIYKLVIEKERTGEYLGKTVQVVPHITDAIQEWVERVAQ 130
            ||||||||||||||.||.|||||||||||:.||:|||.|:|||:|||||||:|||||||:||||.
plant    66 EVDLDLGNYERFLDSTLTRDNNITTGKIYQSVIDKERKGDYLGRTVQVVPHVTDAIQEWIERVAN 130

  Fly   131 TPVQG-SSKPQVCIVELGGTIGDIEGMPFVEAFRQFQFRVKRENFCLAHVSLVPLPKATGEPKTK 194
            .||.| ...|.||::||||||||||.|||:||..||.::|...||||.||||||:....||.|||
plant   131 VPVDGKEGPPDVCVIELGGTIGDIESMPFIEALGQFSYKVGPGNFCLVHVSLVPVLSVVGEQKTK 195

  Fly   195 PTQSSVRELRGCGLSPDLIVCRSEKPIGLEVKEKISNFCHVGPDQVICIHDLNSIYHVPLLMEQN 259
            |||.|||.||..||:|:::.|||.|.:...||.|:|.||||....::.::|:.:|:|||||:..
plant   196 PTQHSVRGLRSLGLTPNILACRSTKALEENVKTKLSQFCHVPEVNIVTLYDVPNIWHVPLLLRD- 259

  Fly   260 GVIEYLNERLQLNIDMSKRTK-CLQQWRDLARRTETVRREVCIAVVGKYTKFTDSYASVVKALQH 323
               :..:|.:...:::|...| .|.:|....:..:|::..|.||:|||||..||||.||:|||.|
plant   260 ---QKAHEAILRELNLSNAIKPDLTEWTARTKIYDTLQDPVRIAMVGKYTGLTDSYLSVLKALLH 321

  Fly   324 AALAVNRKLELVFIESCLLEEETLHSEPSKYHKEWQKLCDSHGILVPGGFGSRGMEGKIRACQWA 388
            |::|.::||.:.::.:..|||.|....|..:...|..|..:.|||||||||.||::|||.|.::|
plant   322 ASVACHKKLVIEWVAASDLEEITAQETPDVHKAAWDLLKGADGILVPGGFGDRGVQGKILATKYA 386

  Fly   389 RENQKPLLGICLGLQAAVIEFARNKLGLKDANTTEIDPNTANALVIDMPEHHTGQLGGTMRLGKR 453
            ||||.|.||||||:|.||:||||:.||..|||:||.:|.|::..:|.|||..|..:|||||||.|
plant   387 RENQVPFLGICLGMQLAVVEFARSILGFHDANSTEFEPETSSPCIIFMPEGSTTHMGGTMRLGSR 451

  Fly   454 ITVFSDGPSVIRQLYGNPKSVQERHRHRYEVNPKYVHLLEEQGMRFVGTDVDKTRMEIIELSGHP 518
            .|.|........:||||.|.|.|||||||||||..:..:|:.|:.|||.|....||||:||..||
plant   452 KTYFQVADCKSAKLYGNAKFVDERHRHRYEVNPDMISEIEKAGLSFVGKDETGRRMEIVELPSHP 516

  Fly   519 YFVATQYHPEYLSRPLKPSPPFLGLILASVDRLNQYIQRGCRLSPRQLSDASSDEEDSVVGLAGA 583
            |||..|:|||:.|||.|||..|||||.|:         .||.              :||:...|
plant   517 YFVGAQFHPEFKSRPGKPSALFLGLIAAA---------SGCL--------------ESVLQTGG- 557

  Fly   584 TKSLSSLKIPITPTNGISKSCNGS 607
                   |:.|...||::   |||
plant   558 -------KVNIVSKNGVA---NGS 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CTPsyn	NP_001287067.1	PLN02327	1..556	CDD:215186	316/556 (57%)
		CTP_synth_N	2..271	CDD:283956	173/269 (64%)
		GATase1_CTP_Synthase	299..544	CDD:153217	134/244 (55%)
emb2742	NP_187873.1	PLN02327	1..555	CDD:215186	320/580 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	368	1.000	Domainoid score	I181
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20446
Inparanoid	1	1.050	638	1.000	Inparanoid score	I187
OMA	1	1.010	-	-		QHG60688
OrthoDB	1	1.010	-	-		D810128at2759
OrthoFinder	1	1.000	-	-		FOG0001109
OrthoInspector	1	1.000	-	-		otm2421
orthoMCL	1	0.900	-	-		OOG6_100470
Panther	1	1.100	-	-	O	PTHR11550
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X676
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980