Protein Alignment Ctps and CTPS2

DIOPT Version :10

• Sequence 1: NP_730023.1
• Gene: Ctps / 39645
• FlyBaseID: FBgn0266452
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: XP_011543847.1
• Gene: CTPS2 / 56474
• HGNCID: 2520
• Length: 628
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 377/574 - (65%)
• Similarity: 455/574 - (79%)
• Gaps: 3/574 - (0%)

  Fly     1 MKYILVTGGVISGVGKGVIASSFGTLLKSCGLDVTSIKIDPYINIDAGTFSPYEHGEVYVLDDGA 65
            |||||||||||||:|||:||||.||:||||||.||:||||||||||||||||||||||:||:||.
Human    43 MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGG 107

  Fly    66 EVDLDLGNYERFLDVTLHRDNNITTGKIYKLVIEKERTGEYLGKTVQVVPHITDAIQEWVERVAQ 130
            ||||||||||||||:.|::||||||||||:.||.|||.|:|||||||||||||||:||||...|:
Human   108 EVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAK 172

  Fly   131 TPVQGS-SKPQVCIVELGGTIGDIEGMPFVEAFRQFQFRVKRENFCLAHVSLVPLPKATGEPKTK 194
            .||.|: .:||:|::|||||||||||||||||||||||:.||||||..||||||...||||.|||
Human   173 VPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKTK 237

  Fly   195 PTQSSVRELRGCGLSPDLIVCRSEKPIGLEVKEKISNFCHVGPDQVICIHDLNSIYHVPLLMEQN 259
            |||:|||.|||.|||||||||||..||.:.||||||.||||.|:|||||||::|.|.||:|:|:.
Human   238 PTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQ 302

  Fly   260 GVIEYLNERLQLNIDMSKRTKCLQQWRDLARRTETVRREVCIAVVGKYTKFTDSYASVVKALQHA 324
            .:::|..|||.|.|..| .:..|.:||::|.|.|.:::...||:||||||..|.||||.|||:|:
Human   303 SIVKYFKERLHLPIGDS-ASNLLFKWRNMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHS 366

  Fly   325 ALAVNRKLELVFIESCLLEEETLHSEPSKYHKEWQKLCDSHGILVPGGFGSRGMEGKIRACQWAR 389
            |||:|.||.|::|:|..||:.|...:|.|:|:.|||||.:.|||||||||.||..||::|..|||
Human   367 ALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKLCKADGILVPGGFGIRGTLGKLQAISWAR 431

  Fly   390 ENQKPLLGICLGLQAAVIEFARNKLGLKDANTTEIDPNTANALVIDMPEHHTGQLGGTMRLGKRI 454
            ..:.|.||:|||:|.||||||||.|.||||::||..||....||||||||:.|.||||||||.|.
Human   432 TKKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRR 496

  Fly   455 TVFSDGPSVIRQLYGNPKSVQERHRHRYEVNPKYVHLLEEQGMRFVGTDVDKTRMEIIELSGHPY 519
            |||....|::|:|||:...::||||||:||||..:...|:..:.|||.|||..|||||||:.|||
Human   497 TVFKTENSILRKLYGDVPFIEERHRHRFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPY 561

  Fly   520 FVATQYHPEYLSRPLKPSPPFLGLILASVDRLNQYIQRGCRLSPR-QLSDASSD 572
            ||..|:|||:.|||:|||||:|||:||:...||.|:|:||:||.. :.||||.|
Human   562 FVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLQQGCKLSSSDRYSDASDD 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctps	NP_730023.1	PLN02327	1..556	CDD:215186	367/555 (66%)
CTPS2	XP_011543847.1	PLN02327	43..599	CDD:215186	367/556 (66%)