Protein Alignment sstn and FRMD4A

DIOPT Version :9

• Sequence 1: NP_648745.1
• Gene: sstn / 39643
• FlyBaseID: FBgn0036476
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_006717520.1
• Gene: FRMD4A / 55691
• HGNCID: 25491
• Length: 1110
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 120/586 - (20%)
• Similarity: 198/586 - (33%)
• Gaps: 138/586 - (23%)

  Fly   122 ARENSSILRRKQSTTSRESRDSQMTINNNNRQ---SETLSNRSSEYDNYQPSSSAGAGDMLVIGV 183
            ||.:..:|...|.:.|.:|....|.....:||   .|||..|..|........:...|.:.|  .
Human   424 ARRHCILLPGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPV--E 486

  Fly   184 AQQQAQQQPPLVKSAL---------KKRPTPTPSQMQYMRQQHQQQAHLAMNMNYQRSQPDVISM 239
            ......::||:|:..:         |..|....::::.:.::...|:.:........|.|:|
Human   487 YPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNV--- 548

  Fly   240 YSANSSNVATLRQPPQVAPQQQPIIVQCDKYYLSPTHQSYNEGGFIKSSQNIKKYVSPMASPSNI 304
                |..:...|:...:...::          |.....:.||.. |||.:...:..|.:....||
Human   549 ----SKKLKKQRKTSYLNALKK----------LQEIENAINENR-IKSGKKPTQRASLIIDDGNI 598

  Fly   305 SYEQQQQRNPLHHQRQLDAISLAPSYVSVDMEAAQHQQQYRWRSQSHIAPLTPPQLGIIEVKSHS 369
            :.|..               ||:.:.|..|.::         :..|.|:||..|..|:
Human   599 ASEDS---------------SLSDALVLEDEDS---------QVTSTISPLHSPHKGL------- 632

  Fly   370 SDMLAVPMPPS--RYPPHDEI----SLSSSSTTIEKKP-KPKQWLESSLDGP-AVIRQMDSQPHS 426
                 .|.|||  |.||...:    .:.......:|.| |||.|.|||||.| ..:::..|..||
Human   633 -----PPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHS 692

  Fly   427 PAGSSNGSSNPGAAAMVSSKPRAKLSSQSMSVAG-RHYSMSNQRP--------TPNYPSASYAVN 482
            .:.....|:...|.|...|.     |.|:..:.| .|::..:..|        :|:|..::.:|:
Human   693 SSHKRFPSTGSCAEAGGGSN-----SLQNSPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVD 752

  Fly   483 TSSKALLS------QSTSYLNAMEQTLG--------------ISVSYPLEPLD------------ 515
            .|...|.|      ..:|.|.:..:.||              ...|...:|:|
Human   753 ISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSE 817

  Fly   516 --IPALRNL---------PPKPSQMQQPTPPPRPPPANQAHTQNQNLSHSGNGSSSGLAHGNAVQ 569
              .||..|.         |.|..|.|:..........:.:.....||:..|....:|.| |..|.
Human   818 HYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGA-GGGVY 881

  Fly   570 TALVSPPVTVATASLSPEIRIESPKNMTVVQ--QATFQPYKEVTKPFEMSDFYKYSTKFKQK-EG 631
            ....|.|.:.......| :.||......||:  ::..:.:..|...|:.|:.|.....||:. .|
Human   882 LHSQSQPSSQYRIKEYP-LYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRG 945

  Fly   632 G 632
            |
Human   946 G 946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sstn	NP_648745.1	None
FRMD4A	XP_006717520.1	B41	54..269	CDD:214604
		FERM_N	57..118	CDD:286467
		FERM_M	140..269	CDD:278785
		FERM_C_FRMD4A_FRMD4B	265..375	CDD:270012
		DUF3338	429..551	CDD:288652	24/130 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900