Protein Alignment sstn and Ezr

DIOPT Version :10

• Sequence 1: NP_648745.1
• Gene: sstn / 39643
• FlyBaseID: FBgn0036476
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_062230.1
• Gene: Ezr / 54319
• RGDID: 621161
• Length: 586
• Species: Rattus norvegicus
• Alignment Length: 223
• Identity: 43/223 - (19%)
• Similarity: 85/223 - (38%)
• Gaps: 42/223 - (18%)

  Fly    43 HSSSSNNNKIEDDPKVRKENLEARKQALEQRLSEKSWLLQQIQKQETAIINGNYEHMTVNEFFVQ 107
            |.......::|.:.| |:|.:|..|   ||.|.||..|:.::|..|........|.....|..:|
  Rat   314 HQKQLERQQLETEKK-RRETVEREK---EQMLREKEELMLRLQDFEQKTKRAEKELSEQIEKALQ 374

  Fly   108 LAQQYKH-EQQLQALARENSSILRRKQSTTSRESRDSQMTINNNNRQSETLS------------- 158
            |.::.:. :::.:.|..:..:.||.|:..    .|.:|..|.:..:.:..|:
  Rat   375 LEEERRRAQEEAERLEADRMAALRAKEEL----ERQAQDQIKSQEQLAAELAEYTAKIALLEEAR 435

  Fly   159 -NRSSEYDNYQPSSSAGAGDMLVIGVAQQQAQQQPPLVKSALKKRPTPTPSQMQYMRQQHQQQAH 222
             .:..|.:.:|..:.....|::       :.:::..||.:|....|.|....:.|         |
  Rat   436 RRKEDEVEEWQHRAKEAQDDLV-------KTKEELHLVMTAPPPPPPPVYEPVNY---------H 484

  Fly   223 LAMNMNYQRSQPDVISMYSANSSNVATL 250
            :...:..:.::|   ..|||..|:...|
  Rat   485 VQEGLQDEGAEP---MGYSAELSSEGIL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sstn	NP_648745.1	None
Ezr	NP_062230.1	B41	7..206	CDD:214604
		[IL]-x-C-x-x-[DE] motif. /evidence=ECO:0000250|UniProtKB:P15311	115..120
		FERM_C_ERM	200..296	CDD:270015
		Interaction with SCYL3. /evidence=ECO:0000250	244..586		43/223 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..338		7/27 (26%)
		ERM_helical	337..456	CDD:466641	23/125 (18%)
		ERM_C	510..586	CDD:459932	43/223 (19%)