Protein Alignment sstn and NF2

DIOPT Version :9

• Sequence 1: NP_648745.1
• Gene: sstn / 39643
• FlyBaseID: FBgn0036476
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_000259.1
• Gene: NF2 / 4771
• HGNCID: 7773
• Length: 595
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 67/337 - (19%)
• Similarity: 128/337 - (37%)
• Gaps: 77/337 - (22%)

  Fly    75 SEKSWLLQQIQKQETAIINGNYEHMTVNEFFVQLA--------QQYKHE----QQLQALARENSS 127
            |:|.:.::.:.| :..:...|...:.||:..:||.        ::.|.:    ||::|.|||..:
Human   267 SDKEFTIKPLDK-KIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKA 330

  Fly   128 ILRRKQSTTSRESRDSQMTINNNNRQSE------------TLSN----RSSE-YDNYQPSSSAGA 175
               |||....|.:|:.||.......:.|            |::|    ||.| .|.....:....
Human   331 ---RKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITE 392

  Fly   176 GDMLVIGVAQQQAQQQPPLVKSALKKRPTPTPSQMQYMRQQHQQQAHLAMNM----NYQRSQPDV 236
            .:..::.....:|:|:...:|:...:    |..:.:.|.|:..:...||:.|    ..:..:.|.
Human   393 EEAKLLAQKAAEAEQEMQRIKATAIR----TEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQ 453

  Fly   237 I--SMYSANSS---------NVATLRQPPQVAPQQQPIIVQCDKYYLSPTHQSYNEGG----FIK 286
            :  .:..|..:         .:||....|.:.|...|         |.|...|:|..|    |..
Human   454 LKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAP---------LPPDIPSFNLIGDSLSFDF 509

  Fly   287 SSQNIKKYVSPMASPSNISYEQ-----QQQRNPLHHQRQLDAISLAPSYVSVDMEAAQHQQQYRW 346
            ...::|: :|.......:.|.:     |:|.|.|  :.:::|:.|.....::|:  ..::...|.
Human   510 KDTDMKR-LSMEIEKEKVEYMEKSKHLQEQLNEL--KTEIEALKLKERETALDI--LHNENSDRG 569

  Fly   347 RSQSH--IAPLT 356
            .|..|  |..||
Human   570 GSSKHNTIKKLT 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sstn	NP_648745.1	None
NF2	NP_000259.1	B41	23..222	CDD:214604
		FERM_C_ERM	216..312	CDD:270015	8/45 (18%)
		PLN03086	307..>367	CDD:178635	15/62 (24%)
		ERM	347..595	CDD:366293	45/253 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900