DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sstn and Frmd7

DIOPT Version :9

Sequence 1:	NP_648745.1	Gene:	sstn / 39643	FlyBaseID:	FBgn0036476	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_001177261.1	Gene:	Frmd7 / 385354	MGIID:	2686379	Length:	703	Species:	Mus musculus

Alignment Length:	419	Identity:	79/419 - (18%)
Similarity:	135/419 - (32%)	Gaps:	126/419 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 QLAQQYKHEQQLQALARENSSILRRKQSTTSRESRDSQMTIN-------NNNRQSETL------- 157
            |...|| ||:|    .|.:..||    |..|::..|.::|..       |....||::
Mouse   327 QYPSQY-HERQ----CRSSPDIL----SDVSKQVEDLRLTYGSSYYRNVNGVHASESMLDSRRRN 382

  Fly   158 -------------SNRSSEYDNYQPSSSAGAGDMLVIGVAQQQAQQQPPLVKSALKKRPTPTPSQ 209
                         |...:|..:..||.|:.:...:   .|.......|..::...::.|..:...
Mouse   383 SAVEVTFAAELEHSKPEAEATSLHPSQSSSSFTFI---YADPVFNTDPEPIEFFEERSPLSSFQT 444

  Fly   210 MQYMRQQHQQQAHLAMNMNYQ-------RSQ-----PDVISMYSANSSNVATLRQPPQVAPQQQP 262
            .......|..:|..|..:.|.       .||     |..:..|         :.:|||| |::..
Mouse   445 TSKFADSHTSKASPARQLTYTDVPYIPCTSQKVDIMPPQVFFY---------VDKPPQV-PRRSL 499

  Fly   263 IIVQCDKYYLSPTHQSYNEGGFIKSSQNIKKYVSPMASPSNISYEQQQQRNPLHHQRQLDAISLA 327
            |:.:.:   :.|  .||.:...||.::.         ||.|:..:..||  .|...::..|.:..
Mouse   500 IMAEEN---MRP--DSYVDHSAIKPAKR---------SPRNMRIKSLQQ--DLQELQEAMARTSG 548

  Fly   328 PSYVSVDMEA------------AQHQQQYRWRSQSHIAPLTPP------QLGIIEVKSHSSDMLA 374
            .|.::|:.|.            .|.|...|.:|||.:..:..|      .||.....:..:|:.|
Mouse   549 RSNINVEPEEEDPHLDDAFAYNLQEQTPKRSQSQSDMKTIRFPFGSEFRPLGPCPALTRKTDLFA 613

  Fly   375 VPMPPSRYPPHDEISLSSSSTTIEKKPKPKQWLESSLDGPAVIRQMD---------SQPHSPAGS 430
            .......:|          :..|::....:.....|.|..:.|.:.|         ..|.:....
Mouse   614 CTFAEQEFP----------TVLIDQSSAERYVASESSDSESEIIKPDYYFLYGKGTKSPRARIRL 668

  Fly   431 SNGS------------SNPGAAAMVSSKP 447
            |:||            :.|||......||
Mouse   669 SSGSLQLEEEDETISFATPGAEDRTLLKP 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sstn	NP_648745.1	None
Frmd7	NP_001177261.1	FERM_F1_FRMD7	1..86	CDD:340708
		FERM_M	85..191	CDD:366056
		FERM_C_FARP1-like	179..299	CDD:270014
		FA	294..330	CDD:370090	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900