Protein Alignment sstn and Frmd4b

DIOPT Version :9

• Sequence 1: NP_648745.1
• Gene: sstn / 39643
• FlyBaseID: FBgn0036476
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001333566.1
• Gene: Frmd4b / 232288
• MGIID: 2141794
• Length: 1035
• Species: Mus musculus
• Alignment Length: 557
• Identity: 105/557 - (18%)
• Similarity: 172/557 - (30%)
• Gaps: 224/557 - (40%)

  Fly    51 KIEDDPKVRKENLEARKQALEQRLSEKSWLLQQIQKQETAIINGNYEHMTVNEFFVQLAQQYKHE 115
            |:..:|.:.|...:.|||.....:..    ||:|:.             ::||:.::..::...:
Mouse   519 KLASEPDLCKTVKKKRKQDYTDAVKR----LQEIEN-------------SINEYRIRCGKKPSQK 566

  Fly   116 QQL----QALARENSSILRRKQSTTSRESRDS-------------------------------QM 145
            ..:    ..:..|:||:   ..:||..:..||                               :.
Mouse   567 AAVVPPEDIIPSESSSL---SDTTTYDDPNDSFTLAGQRPSSVPHSPRILPPKSLGIERIHFRKS 628

  Fly   146 TINN---NNRQS-ETLSNRSSEYDNYQPSSSAGAGDMLVIGVAQQQAQQQPPLVKSALKKRPTPT 206
            :||.   :.|.| |.||..||.|...:.....|           :.....|.|.::|........
Mouse   629 SINEQFMDTRHSREMLSTHSSPYKTLERRPQGG-----------RSMPTTPVLTRNAYSSSHLEP 682

  Fly   207 PSQMQYMRQQH---QQQAHLAMNMN----------YQRSQPDVI----SMYSANSSN----VATL 250
            .|..|:.||:.   :.|:||...|:          .|||....|    |.|::.||:    |...
Mouse   683 DSSSQHCRQRSGSLESQSHLLSEMDSDKPFFTLSKSQRSSSTEILDDGSSYTSQSSSEYYCVTPA 747

  Fly   251 RQP------------------------------PQVAPQQQPI---------------------- 263
            ..|                              |.:| |:.|:
Mouse   748 ASPYYTTQTLDTRARGRRRSKKHSVSTSNSGSMPNLA-QKDPLRNGVYSKGQDPPPSGYYIAGYP 811

  Fly   264 -IVQCDKYYLSPTHQSYNEGGFIKSSQNIKKY-VSP-MASPSNISYEQQQQRNPLHHQRQLD--- 322
             ..:||.||         .||::..:....:| |:| ..|.::..|::|:..:...|:.::|
Mouse   812 PYAECDLYY---------SGGYVYENDTEGQYSVNPSYRSSAHYGYDRQRDYSRSFHEDEVDRVP 867

  Fly   323 ----AISLAPSYVSVDME----------AAQH-----QQQYRWRSQSHIAPLTPPQLGIIEVKSH 368
                |....|...:|..|          .|:|     |:....:.|.| :|.|          |.
Mouse   868 HNPYATLRLPRKAAVKSEHITKNIHKALVAEHLRGWYQRASGQKDQGH-SPQT----------SF 921

  Fly   369 SSDM----------LAVPMPPSRYPPHDEISLSSSSTTIEKKPKPKQWLESSLDGPAVIRQMDSQ 423
            .||.          |.||..||        |.:||.:::........|......|   :.:.::.
Mouse   922 DSDRGSQRCLGFAGLQVPCSPS--------SRASSYSSVSSTNASGNWRTQLTIG---LSEYENP 975

  Fly   424 PHSPAGSSNGS-SNPGAAAMVSSKPRAKLSSQSMSVA 459
            .|||..|..|| .||             |||.|...|
Mouse   976 VHSPYTSYYGSIYNP-------------LSSPSRQYA 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sstn	NP_648745.1	None
Frmd4b	NP_001333566.1	Necessary for adherens junction and tight junction localization. /evidence=ECO:0000269|PubMed:20080746	542..972		86/492 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	563..615		7/54 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	631..699		17/78 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	713..738		6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	754..798		4/44 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	906..926		7/30 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	939..958		6/26 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	994..1035		2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900