Protein Alignment LGALS8 and CG5335

DIOPT Version :10

• Sequence 1: NP_006490.3
• Gene: LGALS8 / 3964
• HGNCID: 6569
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_611349.2
• Gene: CG5335 / 37140
• FlyBaseID: FBgn0034365
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 359
• Identity: 84/359 - (23%)
• Similarity: 132/359 - (36%)
• Gaps: 87/359 - (24%)

Human    19 FVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNG-SSMKPRADVAFHFNPRFKRAGCIVCNTLI 82
            |.|.:...|:.|.::.:.......|.||.::|... |::.|.||:...|:..| |...||.|:.|
  Fly     5 FAGNLSHPLEFGHVLEVVAKTIDGAARFHINLCTAKSTVDPNADIGLRFSCYF-RNDVIVRNSRI 68

Human    83 NEKWGREEI------TYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIY 141
            |..||.||.      |...|....:.|.:.|:..:|.|.:::|.:....:.:|:....|..|.|.
  Fly    69 NGAWGEEESHVMDPNTLPNPIVSGEFFLVYILCCEDSFAISINSREFCRFRYRMPLGTIRALEIR 133

Human   142 GKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLPSNRGGDISKIAPRTVYTKSKDS 206
            .::.:                                            |.::..|||:..
  Fly   134 DQIQV--------------------------------------------IKQVDHRTVFPN---- 150

Human   207 TVNHTLTCTKIPPMNYVSKRLPFAARLNTP---MGPGRTVVVKGEVNANAK-SFNVDLLAGKSKD 267
                        |...|.....|.|..|..   ..||..:|:......|.| .|.:..:...:|.
  Fly   151 ------------PWPAVHASDYFKAFSNDQPILFSPGHVIVLTARCFENKKGQFIIKFMDSDTKR 203

Human   268 IALHLNPRLNIKAFVRNSFLQE-SWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLE 331
            ..||.:.|.:.||.||||..:. .:|.|||: ..|||.....|::.:....||...||:|.:...
  Fly   204 EELHFSVRFDEKAVVRNSMNKNFEFGSEERH-GGFPFVFNQQFKLALAFTEREVLTAVDGYNFFS 267

Human   332 YKHR----------FKELSSIDTL--EINGDIHL 353
            |..|          || ::||:.|  :|.|..||
  Fly   268 YTWRTPNAMMNLVGFK-VTSINGLVVQITGVDHL 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LGALS8	NP_006490.3	Gal-bind_lectin	24..149	CDD:214904	33/131 (25%)
		Gal-bind_lectin	236..356	CDD:214904	40/135 (30%)
CG5335	NP_611349.2	Gal-bind_lectin	12..140	CDD:459768	33/172 (19%)
		GLECT	172..297	CDD:238025	37/126 (29%)