Protein Alignment Sytbeta and SYT12

DIOPT Version :9

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: XP_024304534.1
• Gene: SYT12 / 91683
• HGNCID: 18381
• Length: 487
• Species: Homo sapiens
• Alignment Length: 423
• Identity: 117/423 - (27%)
• Similarity: 185/423 - (43%)
• Gaps: 89/423 - (21%)

  Fly   219 SLPSEPGFPHHLARSPSPMRTISLDARCGS----------PAHSADPGDLRTPSPSQSSLASLAG 273
            |.||...||::..|        .|..:.|.          ||.:|.....|.|...:.||:
Human   113 SFPSPSPFPNYDYR--------YLQQKYGESCAEAREKRVPAWNAQRASTRGPPSRKGSLS---- 165

  Fly   274 GSGMGGSSAGKGVAGGRCLSPLLIPPRSQPGVDPAMGPASPLGALQPDLYRMPDGPVYLTAPESS 338
                                           ::......|.||.|:. :.|..|...|.|..:|.
Human   166 -------------------------------IEDTFESISELGPLEL-MGRELDLAPYGTLRKSQ 198

  Fly   339 HA------------------VGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEGGFRDPYVRLMLQ 385
            .|                  :|::.:.::||.....|.|.:::..:|...||..|...::|:.|.
Human   199 SADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLL 263

  Fly   386 PEVDSRKRQTHIHRGESNPY---FDQHFKFPVSRDQLQGKELILQVLDYDRYSHNDIIGEVRISV 447
            |:    ::...|.|.:.|.|   ||:.|..|:....|:.|.|...|...|....|...|.|.:.:
Human   264 PD----EQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKL 324

  Fly   448 DGLDLS-KSVEIWGDLLRTKKPKEDRPELLCSLNYLPQAERLTVVIMKARNL-----DTLQEPYV 506
            ..|||. :....|..|....|..:...|:|.||:|||.|||||||::||:||     .|..:|:|
Human   325 SVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFV 389

  Fly   507 KIYLIQNGKRIKKKKTSITKSDDPTNPIWNEAFTFNLQSNYLHNAAIEIYVVGAGSE--ATEIGC 569
            |:||:|:|:::.||||:: |.||| ||::|||..|::.:..|.:.::.:.|..:.|:  ...:|.
Human   390 KVYLLQDGRKMSKKKTAV-KRDDP-NPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGH 452

  Fly   570 CGLGPQESGTGCQHWHDMINNARKPTAMWHYIR 602
            ..:||..||.|..||:.|:...|:|.:|||.:|
Human   453 VIIGPSASGMGTTHWNQMLATLRRPVSMWHAVR 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	C2	341..463	CDD:301316	32/125 (26%)
		C2B_Synaptotagmin	473..601	CDD:175975	57/134 (43%)
SYT12	XP_024304534.1	C2	218..329	CDD:326325	29/114 (25%)
		C2B_Synaptotagmin-12	350..485	CDD:176051	57/136 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10024
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920