Protein Alignment Sytbeta and SYT8

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001277261.2
• Gene: SYT8 / 90019
• HGNCID: 19264
• Length: 402
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 126/402 - (31%)
• Similarity: 194/402 - (48%)
• Gaps: 64/402 - (15%)

  Fly   225 GFPHHLARSPSPMRTISLDARCGSPAHSADPG---DL--RTPSPSQSSLASLAGGSGMGGSSAGK 284
            |.|.....:|:|..|            :|.||   ||  .||.|..:.:             ||.
Human    17 GHPPVSPSAPAPAGT------------TAIPGLIPDLVAGTPWPRWALI-------------AGA 56

  Fly   285 GVAGGRCLSPLLIPP-------RSQPGVDPAMGPASPLGA-----LQPDLYRMPDGPVYLTAPES 337
            ..||...:|.||...       |.:|....::|..|..|.     :|||:    ||  ..::|..
Human    57 LAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDV----DG--LESSPGD 115

  Fly   338 SHAVGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEGGFRDPYVRLMLQPEVDSRKRQTHIHRGES 402
            :...|.|.|.:::|:...::.|.|.:|.:|.|   ||..|||.|:.:..:...| .:|.:|||..
Human   116 AQQWGCLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHR-HETKVHRGTL 176

  Fly   403 NPYFDQHFKFPVSRDQLQGKELILQVLDYDRYSHNDIIGEVRISVDGLDLSKSVEIWGDLLRTKK 467
            .|.||:...|.:.:.:|.|..|.:|:.::.|:|.::.:||:|:.:..:||...:|.|..|   ..
Human   177 CPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLL---GP 238

  Fly   468 PKEDRPEL---LC-SLNYLPQAERLTVVIMKARNL-DTLQEPYVKIYLIQNGKRIKKKKTSITKS 527
            |...:||.   || ||.|:|.:.|||||:::||.| ..|.|||||:.|:.|.::.||:||:..|.
Human   239 PAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATKKG 303

  Fly   528 DDPTNPIWNEAFTFNLQSNYLHNAAIEIYVVGAGSE-ATE-IGCCGLGPQESGTGCQHWHDMINN 590
              ...|.:||||||.:..:.:.|..:.:.|...... .|| :|...||.:.||...|||.||:.:
Human   304 --TAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAH 366

  Fly   591 ARKPTAMWHYIR 602
            ||:|.|..|.:|
Human   367 ARRPIAQRHPLR 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039	13/46 (28%)
		C2	341..463	CDD:472691	37/121 (31%)
		C2B_Synaptotagmin	473..601	CDD:175975	55/134 (41%)
SYT8	NP_001277261.2	C2	120..233	CDD:472691	36/116 (31%)
		C2	248..377	CDD:472691	53/130 (41%)