Protein Alignment Sytbeta and SYT15

DIOPT Version :9

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: XP_024303996.1
• Gene: SYT15 / 83849
• HGNCID: 17167
• Length: 474
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 147/550 - (26%)
• Similarity: 224/550 - (40%)
• Gaps: 112/550 - (20%)

  Fly    73 TPPPQPMTPPPSASSVTSTTSGIGSVSAGSVSDSCDLPTDSEEVAIAKECQPIQPASQLHGMHGG 137
            :|.|.|....|.|.....|..|.....:||...:                  ::|::...|...|
Human     6 SPHPAPSRREPLAPLAPGTRPGWSPAVSGSSRSA------------------LRPSTAGPGPGPG 52

  Fly   138 MGLNHHHMGTVSATGTDILRGPAEVFH--SP-LHLHHQSRSFPPRLQRTPSISSQSSVDSAPSRH 199
            .|     .|..:|:|..:   ||...|  :| ....||....||          ..|.|.||.|.
Human    53 TG-----WGGTAASGRWV---PAPAVHCAAPRAAAGHQQHHGPP----------LCSPDGAPRRF 99

  Fly   200 SGHRGS-SPQIRTFGPDGRSSLPSEP-GFPHHLARSPSPMRTISLDARCGSPAHSAD----PGDL 258
            ....|| :|..:|    |.:||..:| |.|..:.....|    :|..|...|.||.:    |.|
Human   100 KRRPGSPAPAAQT----GETSLREQPHGGPPAVPFVVPP----TLQGRDWVPLHSGEWADAPWD- 155

  Fly   259 RTPSPSQSSLASLAGGSGMGGSSAGKGVAGGRCLSPLLIPPRSQPGVDPAMGPASPLGALQPDLY 323
              |.|:..                             |:|..|..|    :|.|..:||:.|:||
Human   156 --PCPASE-----------------------------LLPHTSSGG----LGDACMVGAINPELY 185

  Fly   324 RMPDGPVYLTAPESSHAVGRLHLRVKYDYHLFDLTVHLIEAHNL-SPIEEGGFRDPYVRLMLQPE 387
            :.|:.......|:.  .:|||...|:|:.....|.|.||:|.:| :|.|.   ..|.|:|.|.|:
Human   186 KFPEDKSETDFPDG--CLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET---CSPLVKLYLLPD 245

  Fly   388 VDSRKRQTHIHRGESNPYFDQHFKFPVSRDQLQGKELILQVLDYDRYSHNDIIGEVRISVDGLDL 452
             :.|..|:...|..|||.||:||.|.||...:..:.|...|...||...:.::|:|...:....|
Human   246 -ERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETL 309

  Fly   453 SKSVE--IWGDL-LRTKKPKEDRPELLCSLNYLPQAERLTVVIMKARNLDTLQEP------YVKI 508
            .....  ||.|| ..:.:|..:..:|...|:|.....|||||:::|:.| .|||.      :||:
Human   310 VGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGL-RLQEDRGIVSVFVKV 373

  Fly   509 YLIQNGKRIKKKKTSITKSDDPTNPIWNEAFTFNLQSNYLHNAAIEIYVVG--AGSEATEIGCCG 571
            .|:.:.|.:|.||||.....  .||::||.|:|...:..|..|::.:.||.  .|.::.::|...
Human   374 SLMNHNKFVKCKKTSAVLGS--INPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVV 436

  Fly   572 LGP--QESGTGCQHWHDMINNARKPTAMWH 599
            :||  ...|...:||.:|::..::....||
Human   437 VGPYMYTRGRELEHWDEMLSKPKELVKRWH 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	C2	341..463	CDD:301316	42/125 (34%)
		C2B_Synaptotagmin	473..601	CDD:175975	41/136 (30%)
SYT15	XP_024303996.1	C2A_Synaptotagmin-15-17	202..322	CDD:176036	41/123 (33%)
		C2B_Synaptotagmin-15	332..469	CDD:176054	41/137 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820