DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sytbeta and Pla2g4f

DIOPT Version :9

Sequence 1:	NP_648734.1	Gene:	Sytbeta / 39630	FlyBaseID:	FBgn0261090	Length:	602	Species:	Drosophila melanogaster
Sequence 2:	XP_008760344.1	Gene:	Pla2g4f / 691907	RGDID:	1593370	Length:	860	Species:	Rattus norvegicus

Alignment Length:	463	Identity:	91/463 - (19%)
Similarity:	143/463 - (30%)	Gaps:	170/463 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LPIGE--GSTTPPPQPMTPPPSASSVTSTTSGIGSVSAGSVSDSCDLPTDSEEVAIAKECQPIQP 127
            |.:|:  ..|....||....|....|..|..       .|...:|::.|:.  |.:|..|..||
  Rat   135 LQLGQPYTKTFTQKQPGLTDPKELQVEFTLE-------KSQMPACEVITNG--VLVAHPCLRIQ- 189

  Fly   128 ASQLHGMHGGMGLNHHHMGTVSATGTDILR--GPAEV-------FHSPLHLHHQSRSFPPRLQRT 183
                              |||:...|..|.  |..|:       :..|..:..|..:..|.|..|
  Rat   190 ------------------GTVTGDKTASLGEFGSREIQLAVPGAYEKPQSVPLQPTTVEPGLPAT 236

  Fly   184 ------PSISSQSSVDSAPSRHSGHRGSSPQIRTFGPDGR------SSLP----------SEPGF 226
                  |.:|.:.::.........|.|.|.::.:......      ||||          .|.|.
  Rat   237 FIFHMNPVLSPRLNIALQEKLLVSHSGPSDELESQTSKMEEASILLSSLPLNQESTRLMNLEEGQ 301

  Fly   227 PHHLARSPSPMRTISLDARCGSPAHSADPGDL---------------------RTPSPSQSSLAS 270
            ...| |..:.||:..||.|.|....|   |:|                     ..|...|..:.:
  Rat   302 QVTL-RMKADMRSEDLDLRLGFELCS---GELEFLDKRKQVVSKALQQVMRLSEAPHCDQVPVIA 362

  Fly   271 LAGGSG-------MGGSSAG-------------KGVAGGR-CLSPLLIPPRSQPGVDPAMGPASP 314
            :.|..|       :.||.||             .||:|.. |:|.|.        .||:....:.
  Rat   363 VLGSGGGTRAMTSLYGSLAGLQELGLLDAVTYLSGVSGSSWCISTLY--------KDPSWSQKTL 419

  Fly   315 LGALQPDLYRMPDGPVYLTAPESSHAVGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEGGFRDPY 379
            .|.::....|:....|.:.:||            :::|:..:........|::|      |.|.:
  Rat   420 QGPIRHASARVCSSKVGMLSPE------------RFEYYTREKKTWESRGHSMS------FTDLW 466

  Fly   380 ---VRLMLQPEVDSRK---RQTHIHRGESNPYFDQHFKFPVSRDQLQGKELILQVLDYDRYS--- 435
               :...|..|.:..|   :|..:.:|: |||       |:                   |:
  Rat   467 GLIIEYFLNQEENPAKLSDQQEMVSQGQ-NPY-------PI-------------------YASIN 504

  Fly   436 -HNDIIGE 442
             ||:|.||
  Rat   505 VHNNISGE 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	C2	341..463	CDD:301316	20/112 (18%)
Sytbeta	NP_648734.1	C2B_Synaptotagmin	473..601	CDD:175975
Pla2g4f	XP_008760344.1	C2_cPLA2	46..166	CDD:176001	8/37 (22%)
		Patatin_and_cPLA2	307..854	CDD:299702	50/262 (19%)
		PLAc	313..802	CDD:214474	48/256 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900