Protein Alignment Sytbeta and Syt7

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001385543.1
• Gene: Syt7 / 59267
• RGDID: 62013
• Length: 687
• Species: Rattus norvegicus
• Alignment Length: 691
• Identity: 185/691 - (26%)
• Similarity: 287/691 - (41%)
• Gaps: 136/691 - (19%)

  Fly     9 CWLAHKRIESWSRMAKERVGAVRRVTLDRNSADE-GTP-SGSGASSTAG---------GNGVSVV 62
            |.|.|     |   .:.::|  :|.   :||.:. ||| ||.|......         .|..|.|
  Rat    35 CGLCH-----W---CQRKLG--KRY---KNSLETVGTPDSGRGRGEKKAINDLDRDFWNNNESTV 86

  Fly    63 HILPIGEGSTTPPPQ------PMTP--PP---------SASSVTSTTSGIGSVSAGSVSDS-CDL 109
            .    .:.|:.||.:      |..|  .|         |.:.|.:..:|:.....|.:.:. ..:
  Rat    87 Q----QKWSSYPPKEFILNISPYAPYGDPRLSLNGTLLSGAKVATAAAGLAVEREGRLGEKPAPV 147

  Fly   110 PTDSEEVAIAKECQPIQPAS------------QLHGMHGGMGLNHHHMGTVSATGTDILRGPA-- 160
            |...|:...:....|.:|.|            |.|...|.:.|::....|:| |.|.:...|:
  Rat   148 PPPGEDALRSGGAAPSEPGSSGKAGRGRWRMVQSHLAAGKLNLSNFEDSTLS-TATTLESIPSSA 211

  Fly   161 --------------EVFHSPLHLHHQSRSFPPRLQRTPSISS-QSSVDSAP-------SRHSGHR 203
                          :....||..:.:.|. |.:...:.|:.. |:...|||       .|....:
  Rat   212 GEPKCQRPRTLMRQQSLQQPLSQNQRGRQ-PSQPTTSQSLGQLQAHAASAPGSNPRAYGRGQARQ 275

  Fly   204 GSSPQIRTFGPDGRSSLPSEPGFPHHLARS------------PSPMRTISLDARCGSPAHSADPG 256
            |:|...:.....|||.  |.||...|:...            ...|..:||..........|:..
  Rat   276 GTSAGSKYRAAGGRSR--SNPGSWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDFANIP 338

  Fly   257 DLRTPSPSQSSLASLAGGSGMGGSSAGKGVAGGRCLSPLLIP-----PRSQPGVDPAMGPASPLG 316
            ||:.|...|:..|.  |...:        .|||:.::...:|     ..|....:|....:..:.
  Rat   339 DLQNPGTQQNQNAQ--GDKRL--------PAGGKAVNTAPVPGQTPHDESDRRTEPRSSVSDLVN 393

  Fly   317 ALQPDLYRMPDGPVYLTAPE--SSHAVGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEGGFRDPY 379
            :|..::..:..|.....|.|  |...:||:...|.|::....|||.:::|..|...:..|..||:
  Rat   394 SLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPF 458

  Fly   380 VRLMLQPEVDSRKRQTHIHRGESNPYFDQHFKFP-VSRDQLQGKELILQVLDYDRYSHNDIIGEV 443
            |::.|.|: ...|.:|.:.|...||::::.|.|. ...:::..:.|.||||||||:|.||.||||
  Rat   459 VKIYLLPD-KKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEV 522

  Fly   444 RISVDGLDLSKSVEIWGDLLRTKKPKED----RPELLCSLNYLPQAERLTVVIMKARNLDTL--- 501
            .|.::.:||::....|.||    ||..|    |.|||.||.|.|.|..:.|.|:|||||..:
  Rat   523 SIPLNKVDLTQMQTFWKDL----KPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIG 583

  Fly   502 --QEPYVKIYLIQNGKRIKKKKTSITKSDDPTNPIWNEAFTFNLQSNYLHNAAIEIYVVGAG--S 562
              .:||||::|:...||::|||| :||..: .|||:||:|.|::.:..|....|.|.|:...  |
  Rat   584 GTSDPYVKVWLMYKDKRVEKKKT-VTKKRN-LNPIFNESFAFDIPTEKLRETTIIITVMDKDKLS 646

  Fly   563 EATEIGCCGLGPQESGTG-CQHWHDMINNARKPTAMWHYIR 602
            ....||...|. .:||.| .:||.|||...|:|.|.||.::
  Rat   647 RNDVIGKIYLS-WKSGPGEVKHWKDMIARPRQPVAQWHQLK 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039	61/304 (20%)
		C2	341..463	CDD:472691	43/122 (35%)
		C2B_Synaptotagmin	473..601	CDD:175975	56/135 (41%)
Syt7	NP_001385543.1	PHA03307	106..>311	CDD:223039	39/208 (19%)
		C2A_Synaptotagmin-7	419..543	CDD:176032	44/128 (34%)
		C2B_Synaptotagmin-7	551..686	CDD:176050	57/137 (42%)