Protein Alignment Sytbeta and sytl2b

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: XP_701277.6
• Gene: sytl2b / 572466
• ZFINID: ZDB-GENE-121214-363
• Length: 1737
• Species: Danio rerio
• Alignment Length: 592
• Identity: 118/592 - (19%)
• Similarity: 225/592 - (38%)
• Gaps: 149/592 - (25%)

  Fly    63 HILPIGEGSTTPPPQPMTPPPSASSVTSTTSGIGSVSAGSVSDSCDLPTDSEEVAIAKECQPIQP 127
            |.|.|.|..:.     .||||.|..|....              |...|.|.|...:.:|.|::.
Zfish  1211 HYLGISEDKSM-----YTPPPVAEQVDDFI--------------CTSFTSSPETNHSCKCPPVKT 1256

  Fly   128 ASQLHG------MHGGMGLNHHHMGTVSATGTDILRG-----------PAEVFHSPLHLHHQSRS 175
            ::.:||      ..|.:|   ||:.|  .|..:|::|           .|....|...::|:|
Zfish  1257 STPVHGSPDLQTRSGSLG---HHLTT--QTDGNIIKGIQNRENESLIQKALKRASSRPVYHKS-- 1314

  Fly   176 FPPRLQRTPSISSQSS--VDSAPSRHSGHRGSSPQIRTFGPDGRSSLPSEPGFPHHLARS-PSPM 237
                ::...||:.|..  ..:....|..:..||..::|      |...::|.....|::| ||.:
Zfish  1315 ----MEDISSIARQDQKLKQTDDYMHDNYDASSTHLQT------SFSTADPEHMKKLSKSVPSFL 1369

  Fly   238 RTISLDARCGSPAHSADPGDLRTPSPSQSSL-----ASLAGGSGMGGSSAGKGVAGGRCLSPLLI 297
            .            ..:|.|:..:.|.|:.|:     ......|...||::...|:|
Zfish  1370 E------------KESDGGESDSESSSRGSVPKWNNRQFTNLSNYSGSTSLSSVSG--------- 1413

  Fly   298 PPRSQPGVDPAMGPASPLGALQPDLYRMPDGPVYLTAPESSHAVGRLHLRVKYDYHLFDLTVHLI 362
                        ..||                ||.:...|....|.:...:.|.:.|.:..:.::
Zfish  1414 ------------SVAS----------------VYTSDYNSVDVQGSIQFSLNYVHKLREFHIFVV 1450

  Fly   363 EAHNLSPIEEGGFR-DPYVRLMLQPE-VDSRKRQTHIHRGESNPYFDQHFKFPVSRDQLQGKELI 425
            :..||:.::....| ||||:..|.|: .:..||:|.:.:...||.:::..::.|..:.|..:.|.
Zfish  1451 QCQNLAAVDAKRNRSDPYVKSYLIPDPANLGKRKTAVKKKTLNPTYNEILRYRVRMEYLTSQVLN 1515

  Fly   426 LQVLDYDRYSHNDIIGEVRISVDGLDLS---------KSVEIWGDLLRTKKPKEDRPELLCSLNY 481
            |.....|.:..|..:||:.:.:...|.:         |...::.....:.:|.:.:.::..::.:
Zfish  1516 LSAWHNDMFGRNSFLGEIELDLSTWDFNDTERKLLPLKPRNLFIQTTNSLQPSDLKGQMRLAIRF 1580

  Fly   482 LPQ---------AERLTVVIMKARNLDTLQ----EPYVKIYLIQNGKRIKKKKTSITKSDDPTNP 533
            |||         :..:.:.:...:||..::    :||||.:::.:..:..::||.:.|.  .|||
Zfish  1581 LPQISHSKNVPGSGEVHIWVKDCKNLPLIRSPTIDPYVKCFVLPDTSKKSRQKTRVLKR--TTNP 1643

  Fly   534 IWNEAFTFN-LQSNYLHNAAIEIYVVGAGSEAT-EIGCCGLGPQESGTGCQH-----WHDMINNA 591
            |:|....:: .::..|..|.:|:.|......|: .:|...||   .|||..:     |.|   :.
Zfish  1644 IFNHTMVYDGFRAEDLKEACVELTVWDRDRLASHSLGGLRLG---MGTGRSYGVQVDWMD---ST 1702

  Fly   592 RKPTAMW 598
            .:..|:|
Zfish  1703 TEEVALW 1709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039	47/223 (21%)
		C2	341..463	CDD:472691	27/132 (20%)
		C2B_Synaptotagmin	473..601	CDD:175975	32/146 (22%)
sytl2b	XP_701277.6	PHD_SF	5..>47	CDD:473978
		C2	1429..1553	CDD:472691	26/123 (21%)
		C2B_SLP_1-2-3-4	1571..1727	CDD:175987	32/147 (22%)