Protein Alignment Sytbeta and Syt10

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_061273.1
• Gene: Syt10 / 54526
• MGIID: 1859546
• Length: 523
• Species: Mus musculus
• Alignment Length: 517
• Identity: 146/517 - (28%)
• Similarity: 224/517 - (43%)
• Gaps: 91/517 - (17%)

  Fly   121 ECQPIQPASQLHGMHGGMGLNHHHMGT----------VSATGTDILRGPAEVFHSPLHLHHQSRS 175
            :|..|.||.: .|..||        ||          ||..|..:|.....||........:|:.
Mouse    33 KCSGIFPADR-SGQGGG--------GTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKL 88

  Fly   176 FPPRLQRTPSISSQSSVDSAPS-------RHSGHRGSSPQIRTFGPDGRSS-----LPSE--PGF 226
            ..|.|...|     .|:.|||:       :........|..:...|..:.|     :|:|  ...
Mouse    89 VAPNLSVLP-----QSISSAPTEVFETEEKKEVEENEKPAPKAIEPAIKISHTSPDIPAEVQTAL 148

  Fly   227 PHHLARSPSPMRTISLDARCGSPAHSADPGDLRTPSPSQSSLASLAGGSGMGGSSAGKGVAGGRC 291
            ..||.:.....|..:      .|..|:.....|...|.|.:::|:....|
Mouse   149 KEHLIKHARVQRQTT------EPTSSSRHNSFRRHLPRQMNVSSVDFSVG--------------- 192

  Fly   292 LSPLLIPPRSQPGVDPAMGPASPLGALQPDLYRMPDGPVYLTAPESSHAVGRLHLRVKYDYHLFD 356
            ..|:|     |.|     ...:.:|.::|:||:...........:.....|:|:..::|||....
Mouse   193 TEPIL-----QRG-----ETRTSIGRIKPELYKQKSVDSEGNRKDDVKTCGKLNFALQYDYENEL 247

  Fly   357 LTVHLIEAHNLSPIEEGGFRDPYVRLMLQPEVDSRKRQTHIHRGESNPYFDQHFKFPVSRDQLQG 421
            |.|.:|:|.:|...:..|..||||::.|.|: ..:|.||.:||...||.||:.|:|||..|||..
Mouse   248 LVVKIIKALDLPAKDFTGTSDPYVKIYLLPD-RKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSN 311

  Fly   422 KELILQVLDYDRYSHNDIIGEVRISVDGL----DLSKSVEIWGDLLRTKKPKEDRPELLCSLNYL 482
            ::|...:.|:||:|.:|:||||  .:|.|    |||:...:|.|:........|..|::.||.||
Mouse   312 RKLHFSIYDFDRFSRHDMIGEV--ILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYL 374

  Fly   483 PQAERLTVVIMKARNLDTL-----QEPYVKIYLIQNGKRIKKKKTSITKSDDPTNPIWNEAFTFN 542
            |.|.|:|:.::|.|||..:     .:||||:.|:..|:|:||:||:..|  :..||::|||..|:
Mouse   375 PTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKK--NTLNPVYNEAIIFD 437

  Fly   543 LQSNYLHNAAIEIYV-----VGAGSEATEIGCCGLGPQESGTGCQHWHDMINNARKPTAMWH 599
            :....:...::.|.|     ||...   .||.|..|....|.|..||::|:...|||...||
Mouse   438 IPPENVDQVSLCIAVMDYDRVGHNE---VIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWH 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039	36/169 (21%)
		C2	341..463	CDD:472691	50/125 (40%)
		C2B_Synaptotagmin	473..601	CDD:175975	49/137 (36%)
Syt10	NP_061273.1	Cysteine motif. /evidence=ECO:0000250|UniProtKB:O35681	13..35		0/1 (0%)
		C2A_Synaptotagmin-1-5-6-9-10	231..356	CDD:176031	50/127 (39%)
		C2B_Synaptotagmin-3-5-6-9-10	365..498	CDD:176048	49/137 (36%)