Protein Alignment Sytbeta and Syt5

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001347350.1
• Gene: Syt5 / 53420
• MGIID: 1926368
• Length: 386
• Species: Mus musculus
• Alignment Length: 380
• Identity: 129/380 - (33%)
• Similarity: 206/380 - (54%)
• Gaps: 37/380 - (9%)

  Fly   247 GSPAHSADPGDLRTPSPSQSS--LASLAGGSGMGGSSAGKGVAGGRCLSPLLIPPRSQPGVDPAM 309
            ||||....|...|....:..:  ||::..|||:...|:...:...||...:  ..:||......:
Mouse     9 GSPAPKTPPDSSRIRQGAVPAWVLATIVLGSGLLVFSSCFCLYRKRCRRRM--GKKSQAQAQVHL 71

  Fly   310 GPASPLG-----ALQPDLYRMPDGPVYLTAP----ESSHAVGRLHLRVKYDYHLFDLTVHLIEAH 365
            .....||     .:||::..:...|   :.|    ...|.:|||...:.||:....|.|.:::|.
Mouse    72 QEVKELGRSYIDKVQPEIEELDRSP---SMPGQQVSDKHQLGRLQYSLDYDFQTGQLLVGILQAQ 133

  Fly   366 NLSPIEEGGFRDPYVRLMLQPEVDSRKR-QTHIHRGESNPYFDQHFKFPVSRDQLQGKELILQVL 429
            .|:.::.||..||||.:.|.|  |.|:| :|.:||...||:|.:.|.|.|...:|.|:.|::.|.
Mouse   134 GLAALDLGGSSDPYVSVYLLP--DKRRRHETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVY 196

  Fly   430 DYDRYSHNDIIGEVRISVDGLDLSKSVEIWGDLLRTKKPKEDRPEL--LC-SLNYLPQAERLTVV 491
            |:||:|.||.|||||:.:..::|.:.|:.|.:|  ...|||::.:|  :| ||.|:|.|.:|||:
Mouse   197 DFDRFSRNDAIGEVRVPMSSVNLGRPVQAWREL--QVAPKEEQEKLGDICFSLRYVPTAGKLTVI 259

  Fly   492 IMKARNLDT-----LQEPYVKIYLIQNGKRIKKKKTSITKSDDPTNPIWNEAFTFNLQSNYLHNA 551
            :::|:||..     |.:||||::|:|.||:::||||:|.|  :..||.:||||:|.:..:.:...
Mouse   260 VLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKK--NTLNPYYNEAFSFEVPCDQVQKV 322

  Fly   552 AIEIYVVG----AGSEATEIGCCGLGPQESGTGCQHWHDMINNARKPTAMWHYIR 602
            .:|:.|:.    ..:||  ||...:|....|.|.:||.||:.|.|:|.|.||.:|
Mouse   323 QVELTVLDYDKLGKNEA--IGRVAVGAAVGGAGLRHWADMLANPRRPIAQWHSLR 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039	6/19 (32%)
		C2	341..463	CDD:472691	47/122 (39%)
		C2B_Synaptotagmin	473..601	CDD:175975	54/139 (39%)
Syt5	NP_001347350.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		5/11 (45%)
		Syt1_2_N	6..76	CDD:425364	16/68 (24%)
		C2	108..230	CDD:472691	48/125 (38%)
		C2	240..374	CDD:472691	54/137 (39%)