Protein Alignment Sytbeta and Sytl1

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_113570.2
• Gene: Sytl1 / 269589
• MGIID: 1933365
• Length: 568
• Species: Mus musculus
• Alignment Length: 579
• Identity: 122/579 - (21%)
• Similarity: 222/579 - (38%)
• Gaps: 127/579 - (21%)

  Fly    75 PPQPMTPPPSASSVTSTTSGIGSVS------AGSVSDSCDLPTDS-----EEVAIAKECQPIQPA 128
            |..||...|.     |...|:..:|      ..::||.  |..|:     ||..::|....::..
Mouse    16 PSLPMAHGPG-----SEAEGLLDLSFLTEEEQEAISDV--LKRDAHLRQLEEGRVSKLRASLEDP 73

  Fly   129 SQLHGMHG-----GMGLNHHHMGTVSATGTDILRGPAEVFHSP-----LHLHHQSRSFPPR-LQR 182
            .||..:.|     .....|||    :..|:|::|.......||     |....::.:.... ::.
Mouse    74 WQLKILTGDWFQEARSQRHHH----AHFGSDLVRASIRRKKSPKGDQALGSDGEAEAAGENTIEG 134

  Fly   183 TPSISSQSSVD-SAPSRHSGHRGS---SPQIRTFGPDGRSSLPSE-------PGFPHHLARSPSP 236
            .|  .|:.|:: :||.|::..:|.   ||.:.:...:|:...|.:       ||..........|
Mouse   135 EP--ESRVSIEVAAPERNTETQGPDLFSPYVPSKASEGQEEEPQDQECELEAPGEGGVQVAEADP 197

  Fly   237 MRTISLDARCGSPAHSADPGDLRTPSPSQSSLASLAGGS---GMGGSSAGKGVAGGRCLSPLLIP 298
                .||     |...|:.....||:.|:::...|..|.   |:|
Mouse   198 ----ELD-----PEQKAEQESQPTPAQSKATSKILENGEEAPGLG-------------------- 233

  Fly   299 PRSQPGVDPAMGPASPLGALQPDLYRMPDGPVYLTAPESSHAVGRLHLR------VKYDYHLFDL 357
                |.:|..:..:|.:.:|.....   .|.:...:.|:.  .|.:.:|      ::|:....:|
Mouse   234 ----PSLDRMLSSSSSVSSLNSSTL---SGSLMSLSGEAE--AGTVQVRGSVLFSLRYEPGTSEL 289

  Fly   358 TVHLIEAHNLSPIEEGGFRDPYVRLMLQPEVDSRKRQTHIHRGESNPYFDQHFKFPVSRDQLQGK 422
            .|.:|:...|:...... .||||:..|.|:..| ||:|.:.:...||.|::..:..|.:..|.|:
Mouse   290 RVQVIQCQGLAAARRRR-SDPYVKSYLLPDKQS-KRKTSVKKRNLNPIFNETLRHSVQQADLPGR 352

  Fly   423 ELILQVLDYDRYSHNDIIGEVRISVDGLDLSKSVEIWGDLLRTKKPKED----RPELLCSLNYL- 482
            .|.|.|...:....|..:|||.:.:|..:.. |...|..|.....|..|    |..|..||.|:
Mouse   353 VLSLSVWHRESLGRNIFLGEVEVPLDTWNWD-SEATWLPLQPRVPPSPDELPSRGLLSLSLKYVP 416

  Fly   483 --------PQAERLTVVIMKARNLDTLQ----EPYVKIYLIQNGKRIKKKKTSITKSDDPTNPIW 535
                    ||:..|...:.:|::|..|:    :.|::..::.:..|..:::|.:.:..  .:|::
Mouse   417 AGSEGGGQPQSGELHFWVKEAQSLVPLRPGSLDTYIQCSVLPDDSRASRQRTRVVRRS--LSPVF 479

  Fly   536 NEAFTFN-LQSNYLHNAAIEIYVVGAGSEAT-EIGCCGLGPQES-GTGCQH-----WHD 586
            |....:: .....|..|..|:.:...|:.|: ::|    |.:.| |||..:     |.|
Mouse   480 NHTMVYDGFGPADLRQACAELSLWDHGALASRQLG----GTRLSLGTGSSYGLQVPWMD 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039	47/224 (21%)
		C2	341..463	CDD:472691	33/127 (26%)
		C2B_Synaptotagmin	473..601	CDD:175975	28/135 (21%)
Sytl1	NP_113570.2	PHD_SF	35..>90	CDD:473978	11/56 (20%)
		NESP55	<92..230	CDD:115071	32/152 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..255		33/189 (17%)
		C2	273..392	CDD:472691	32/121 (26%)
		C2B_SLP_1-2-3-4	405..561	CDD:175987	29/136 (21%)