Protein Alignment Sytbeta and Syt1

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001028852.2
• Gene: Syt1 / 25716
• RGDID: 3803
• Length: 421
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 103/279 - (36%)
• Similarity: 163/279 - (58%)
• Gaps: 17/279 - (6%)

  Fly   335 PESSHAVGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEGGFRDPYVRLMLQPEVDSRKRQTHIHR 399
            |:....:|:|...:.||:....|.|.:|:|..|..::.||..||||::.|.|: ..:|.:|.:||
  Rat   136 PKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD-KKKKFETKVHR 199

  Fly   400 GESNPYFDQHFKFPVSRDQLQGKELILQVLDYDRYSHNDIIGEVRISVDGLDLSKSVEIWGDLLR 464
            ...||.|::.|.|.|...:|.||.|::.|.|:||:|.:|||||.::.::.:|.....|.|.||..
  Rat   200 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQS 264

  Fly   465 TKKPKEDRPELLC-SLNYLPQAERLTVVIMKARNLDT-----LQEPYVKIYLIQNGKRIKKKKTS 523
            .:|.::::...:| ||.|:|.|.:|||||::|:||..     |.:|||||:|:|||||:|||||:
  Rat   265 AEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT 329

  Fly   524 ITKSDDPTNPIWNEAFTFNLQSNYLHNAAIEIYV-----VGAGSEATEIGCCGLGPQESGTGCQH 583
            |.|  :..||.:||:|:|.:....:....:.:.|     :|...   .||...:|...:|...:|
  Rat   330 IKK--NTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKND---AIGKVFVGYNSTGAELRH 389

  Fly   584 WHDMINNARKPTAMWHYIR 602
            |.||:.|.|:|.|.||.::
  Rat   390 WSDMLANPRRPIAQWHTLQ 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039
		C2	341..463	CDD:472691	45/121 (37%)
		C2B_Synaptotagmin	473..601	CDD:175975	55/138 (40%)
Syt1	NP_001028852.2	Syt1_N	5..112	CDD:409248
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..141		1/4 (25%)
		Phospholipid binding. /evidence=ECO:0000305	135..381		92/250 (37%)
		C2A_Synaptotagmin-1-5-6-9-10	142..264	CDD:176031	46/122 (38%)
		C2B_Synaptotagmin-1	273..408	CDD:176047	55/139 (40%)