Protein Alignment Sytbeta and Syt3

DIOPT Version :9

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001107588.1
• Gene: Syt3 / 20981
• MGIID: 99665
• Length: 587
• Species: Mus musculus
• Alignment Length: 534
• Identity: 160/534 - (29%)
• Similarity: 228/534 - (42%)
• Gaps: 127/534 - (23%)

  Fly   125 IQPASQLHGMHGGMGLNHHHMGTVSATGTDILRGPAEVFHSPLHLHHQSRSFPPRLQ-------- 181
            :.|...|.|:.||.|   ||:| .|..|..:|.||        |.|..:...||..:
Mouse   101 LAPGVGLAGLVGGGG---HHLG-ASLGGHPLLGGP--------HHHGHTAHHPPFAELLEPGGLG 153

  Fly   182 -RTPSISSQSSVDSAPSR------HSGHRGS--SPQIRTFGPDGRSSL---PSEPGFP----HHL 230
             ..|...|...:||.|..      .:|.:.|  ||::.:.|..|...|   ||..|.|    |..
Mouse   154 GSEPPEPSYLDMDSYPEAAVASVVAAGVKPSQTSPELPSEGGTGSGLLLLPPSGGGLPSAQSHQQ 218

  Fly   231 ARS----------PSPM--RTISLDARCGSPAHSADPGDLRTPSPSQSSLASLAG--------GS 275
            ..|          |.|:  :|::..|   .|:....|..|..|.|.....|.|.|        |:
Mouse   219 VTSLAPTTRYPALPRPLTQQTLTTQA---DPSTEERPPALPLPLPGGEEKAKLIGQIKPELYQGT 280

  Fly   276 GMGG-SSAGKGVAGGRCLSPLLIPPRSQPGVDPAMGPASPLGALQPDLYRMPDGPVYLTAPESSH 339
            |.|| ...|.|.||..|
Mouse   281 GPGGRRGGGSGEAGAPC------------------------------------------------ 297

  Fly   340 AVGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEGGFRDPYVRLMLQPEVDSRKRQTHIHRGESNP 404
              ||:...::|.|....|.|.:::|.:|...:..||.||||::.|.|: ..:|.||.:||...||
Mouse   298 --GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD-RKKKFQTKVHRKTLNP 359

  Fly   405 YFDQHFKFPVSRDQLQGKELILQVLDYDRYSHNDIIGEVRISVDGLDLSKSV---EIWGDLLRTK 466
            .|::.|:|.|...:|..::|...|.|:||:|.:|:||:|.:. :.|:|::..   .:|.|:|...
Mouse   360 IFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRPLWRDILEGG 423

  Fly   467 KPKEDRPELLCSLNYLPQAERLTVVIMKARNLDTL-----QEPYVKIYLIQNGKRIKKKKTSITK 526
            ..|.|..||..||.|||.|.||||.|:||.||..:     .:||||..||..|:|:||:||||.|
Mouse   424 SEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 488

  Fly   527 SDDPTNPIWNEAFTFNLQSNYLHNAAIEIYVVG---AGSEATEIGCCGLGPQESGT-GCQHWHDM 587
              :..||.:|||..|::....:.|..:.|.||.   .|.... ||.|.:||:.:.. |.:||.:|
Mouse   489 --NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEV-IGVCRVGPEAADPHGREHWAEM 550

  Fly   588 INNARKPTAMWHYI 601
            :.|.|||...||.:
Mouse   551 LANPRKPVEHWHQL 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	C2	341..463	CDD:301316	42/124 (34%)
		C2B_Synaptotagmin	473..601	CDD:175975	58/136 (43%)
Syt3	NP_001107588.1	Cysteine motif. /evidence=ECO:0000269|PubMed:10531343	10..34
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..258		19/77 (25%)
		C2A_Synaptotagmin-1-5-6-9-10	297..421	CDD:176031	43/175 (25%)
		C2B_Synaptotagmin-3-5-6-9-10	430..564	CDD:176048	58/136 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.780