DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sytbeta and Y48G8AR.2

DIOPT Version :9

Sequence 1:	NP_648734.1	Gene:	Sytbeta / 39630	FlyBaseID:	FBgn0261090	Length:	602	Species:	Drosophila melanogaster
Sequence 2:	NP_490838.3	Gene:	Y48G8AR.2 / 171702	WormBaseID:	WBGene00021693	Length:	339	Species:	Caenorhabditis elegans

Alignment Length:	383	Identity:	80/383 - (20%)
Similarity:	125/383 - (32%)	Gaps:	125/383 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RIESWSRMAKERVGAVRRVTLD---RNSADEGTPSG-SGASSTAGGNGVSVVHILPIGEGSTTPP 75
            ||.|.|...     |:::.:|.   |.|:..|:.|. ||.||.  ||         :..|.|:|.
Worm    41 RIRSLSTCV-----AIKKTSLQEKRRASSVAGSESSESGLSSP--GN---------VSHGRTSPL 89

  Fly    76 PQPMTPPPSASSVTSTTSGIGSV-SAGSVSDSCDLPTDSEEVAIAKECQPIQPASQLHGMHGGMG 139
            |:......|....|     :|.: ::|:....|       ...|..:|        .|.:..|..
Worm    90 PKWNNRLCSTCQCT-----LGYILNSGTKCKKC-------SSHICDKC--------AHSVSSGSA 134

  Fly   140 LN--HHHMGTV-------SATGTDILRGPAEVFHSPLHLHHQSRSFPPRLQRTPSISSQSSVDSA 195
            .|  .:.:.||       ||...:.::|..|.          .::....|....|...::|| ..
Worm   135 QNPQKYSLCTVCYSERELSAAKNEWVQGSDEA----------EKTSEQLLNVMKSSEKRNSV-QI 188

  Fly   196 PSRHSGHRGSSPQIRTFGPDGRSSLPS-----------EPGF-----------PHHLARSPSPMR 238
            |:.....:|.:|..|..      :||:           |||.           |.....||||.
Worm   189 PATPPAVKGKAPYKRNL------TLPAIQTSYLSVPDEEPGLVQSAGGNSNFSPKFWGGSPSPR- 246

  Fly   239 TISLDARCGSPAHSADPGDLRTPSPSQSSLASLAGGSGMGGSSAGKGVAGGRCLSPLLIPPRSQP 303
                ..|..|.|:|::. .:.:|:....||.:|                          .||...
Worm   247 ----SPRSFSSANSSNI-SINSPAAPNDSLRAL--------------------------HPREAI 280

  Fly   304 GVDPAMGPAS--PLGALQPD-LYRMPDGPVYLTAPESSHAVGRLHLRVKYDYHLFDLT 358
            | .||..|.|  ||..:..| ..::|......:|.|.|...|:|..:.:.....|.|:
Worm   281 G-SPAPRPMSSTPLSGVPEDSTIQIPQVERRRSAFEGSRRSGKLRRQSEATVPTFQLS 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	C2	341..463	CDD:301316	4/18 (22%)
Sytbeta	NP_648734.1	C2B_Synaptotagmin	473..601	CDD:175975
Y48G8AR.2	NP_490838.3	PHD_SF	15..159	CDD:389947	34/153 (22%)
Y48G8AR.2	NP_490838.3	FYVE_Slp3_4_5	95..148	CDD:277286	12/72 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900