Protein Alignment Sytbeta and SYT9

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: XP_011518202.1
• Gene: SYT9 / 143425
• HGNCID: 19265
• Length: 567
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 109/302 - (36%)
• Similarity: 164/302 - (54%)
• Gaps: 28/302 - (9%)

  Fly   315 LGALQPDLYRM-----PDGPVYLTAPESSHAVGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEGG 374
            :|.::|:||:.     .||     ...:|.|.|:|:..:|||..|..|.|.:.:|.||...:..|
Human   195 IGRIKPELYKQRSLDNDDG-----RRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSG 254

  Fly   375 FRDPYVRLMLQPEVDSRKRQTHIHRGESNPYFDQHFKFPVSRDQLQGKELILQVLDYDRYSHNDI 439
            ..||||::.|.|: ...|.||.:||...||.||:.|.|||..:.|:.::|...|.|:||:|.:|:
Human   255 TSDPYVKIYLLPD-RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDL 318

  Fly   440 IGEVRIS--VDGLDLSKSVEIWGDLLRTKKPKEDRPELLCSLNYLPQAERLTVVIMKARNLDTL- 501
            ||:|.:.  :|..|..:...:|.|:........|..||:.||.|||.|.|||:.|:|||||..:
Human   319 IGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMD 383

  Fly   502 ----QEPYVKIYLIQNGKRIKKKKTSITKSDDPTNPIWNEAFTF-----NLQSNYLHNAAIEIYV 557
                .:||||:.|:.:|:|:||:|||..:  :..||::|||..|     |:...:|..|.::...
Human   384 ITGASDPYVKVSLMCDGRRLKKRKTSTKR--NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDR 446

  Fly   558 VGAGSEATEIGCCGLGPQESGTGCQHWHDMINNARKPTAMWH 599
            ||...   .||.|.:|.:....|..||.:|::..|||.|.||
Human   447 VGHNE---IIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWH 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039
		C2	341..463	CDD:472691	46/123 (37%)
		C2B_Synaptotagmin	473..601	CDD:175975	54/137 (39%)
SYT9	XP_011518202.1	C2	221..345	CDD:472691	46/124 (37%)
		C2B_Synaptotagmin-3-5-6-9-10	354..487	CDD:176048	54/137 (39%)