Protein Alignment Sytbeta and Doc2a

DIOPT Version :9

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001355284.1
• Gene: Doc2a / 13446
• MGIID: 109446
• Length: 405
• Species: Mus musculus
• Alignment Length: 414
• Identity: 111/414 - (26%)
• Similarity: 174/414 - (42%)
• Gaps: 83/414 - (20%)

  Fly   229 HLARS--PSPMRTISLDARCGSPAHSADPGDLRTPSPSQSSLASLAGGSGMGGSSAGKGVAGGRC 291
            |:|.:  |.|:|.|         ...:|....|.|.|.        ||.|.||:..|:..|.
Mouse    16 HMAINVCPGPIRPI---------RQISDYFPRRGPGPE--------GGGGGGGTGCGEAPAH--- 60

  Fly   292 LSPLLIPPRSQPGVDPAMGPASPLGALQPDLYRMPDG-PVYLTAPESSHAVGRLHLRVKYDYHLF 355
            |:||.:.|           ||:.|||..||     || .|.....:.:.|:|.|...:.||....
Mouse    61 LAPLALAP-----------PAALLGATTPD-----DGAEVDSYDSDDTTALGTLEFDLLYDQASC 109

  Fly   356 DLTVHLIEAHNLSPIEEGGFRDPYVRLMLQP-EVDSRKRQTHIHRGESNPYFDQHFKFP-VSRDQ 418
            .|...::.|..|.|::..|..||||:|.|.| ...:.|.:|...|...||.:::...:. ::.|.
Mouse   110 MLHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYSGITDDD 174

  Fly   419 LQGKELILQVLDYDRYSHNDIIGEVRISVDGLDLSK--------------------SVEIWGDLL 463
            :..|.|.:.|.|.|:.|||:.|||:|:.:..|..|:                    |..:.|...
Mouse   175 ITHKVLRISVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLPSPSSMSAALRGISC 239

  Fly   464 RTKKPK---------EDRPELLCSLNYLPQAERLTVVIMKARNLDTL-----QEPYVKIYLIQNG 514
            ..|:.:         |:|..:|.||:|..:...|.|.|::..:|..:     .:||||.||..:.
Mouse   240 YLKELEQAEQGPGLLEERGRILLSLSYSSRRHGLLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDV 304

  Fly   515 KRIKKKKTSITKSDDPTNPIWNEAFTFNLQSNYLHNAAIEI----YVVGAGSEATEIGCCGLGPQ 575
            .:..|.||.:.|.  ..||.:||.|.:.::.:.|....:|:    |.:|..::.  ||...|||.
Mouse   305 DKKSKHKTCVKKK--TLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDF--IGGVSLGPG 365

  Fly   576 ESGTGCQHWHDMINNARKPTAMWH 599
            ..|...:||:|.::........||
Mouse   366 ARGEAQKHWNDCLHQPDTALERWH 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	C2	341..463	CDD:301316	38/143 (27%)
		C2B_Synaptotagmin	473..601	CDD:175975	38/136 (28%)
Doc2a	NP_001355284.1	Interaction with UNC13D and DYNLT1. /evidence=ECO:0000250	1..94		31/113 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..54		9/27 (33%)
		C2A_Rabphilin_Doc2	95..218	CDD:176000	36/122 (30%)
		Interaction with UNC13D. /evidence=ECO:0000250	220..405		43/174 (25%)
		C2B_Rabphilin_Doc2	259..391	CDD:176030	38/135 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910