Protein Alignment Sytbeta and Syt17

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001390574.1
• Gene: Syt17 / 110058
• MGIID: 104966
• Length: 474
• Species: Mus musculus
• Alignment Length: 455
• Identity: 135/455 - (29%)
• Similarity: 198/455 - (43%)
• Gaps: 77/455 - (16%)

  Fly   176 FPPRLQRTPSISSQSSVDSAPSRHSGHRGSSPQI--RTFGPDGRSSLPSEPGFPHHLARSPSPMR 238
            ||  .|..|.:.:..|.|.  ...|.|..|...:  ||..||||.|........:.|.|     |
Mouse    53 FP--AQTPPWLMASRSNDK--DGDSVHTASDVPLTPRTNSPDGRRSSSDTSKSTYSLTR-----R 108

  Fly   239 TISLDA-RCGSPAHSADPGDLRTPSPSQSSLASLAGGSGMGGSSAGKGVAGGRCLSPLLIPPRSQ 302
            ..|||: |..||.....|.:....|..:.|:                                 |
Mouse   109 ISSLDSRRPSSPLIDIKPVEFGVLSAKKESI---------------------------------Q 140

  Fly   303 PGV-DPAMGPASPLGALQPDLYRMP---DGPVYLTAPE--SSHAVGRLHLRVKYDYHLFDLTVHL 361
            |.| .....|.......:|.||.:.   |....||..|  |.:.:|.||...:||.....|||.:
Mouse   141 PSVLRRTYTPDDYFRKFEPRLYSLDSNLDDVDSLTDEEIMSKYQLGMLHFSTQYDLLHNHLTVRV 205

  Fly   362 IEAHNL-SPIEEGGFR------DPYVRLMLQPEVDSRKRQTHIHRGESNPYFDQHFKFPVSRDQL 419
            |||.:| .||...|.|      :|||::.|.|: ....:||.:.|....|.|::.:.|.:...:.
Mouse   206 IEARDLPPPISHDGSRQDMAHSNPYVKICLLPD-QKNSKQTGVKRKTQKPVFEERYTFEIPFLEA 269

  Fly   420 QGKELILQVLDYDRYSHNDIIGEVRISVDGLDLSKSVEIWGDLLRTKKPKEDRPELLCSLNYLPQ 484
            |.:.|:|.|:|:|::|.:.:||:|.:.:..:||.|....|..|:.:.:.:.:..|||.||||||.
Mouse   270 QRRTLLLTVVDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPS 334

  Fly   485 AERLTVVIMKARNL---DTLQ--EPYVKIYLIQNGKRIKKKKTSITKSDDPTNPIWNEAFTFNLQ 544
            |.||.|.|::|:.|   |..|  :|:|||.|:...|.:|.||||..:.  ..:|.:||:|:|.:.
Mouse   335 AGRLNVDIIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRG--TIDPFYNESFSFKVP 397

  Fly   545 SNYLHNAAIEIYVVGAGSEATE-------IGCCGLGPQESGTGCQHWHDMINNARKPTAMWHYIR 602
            ...|.||::...|.|...:::.       ||....||.||    .||..|:|..|.....||.:|
Mouse   398 QEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSES----NHWRRMLNTHRTAVEQWHSLR 458

  Fly   603  602
            Mouse   459  458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039	27/93 (29%)
		C2	341..463	CDD:472691	41/128 (32%)
		C2B_Synaptotagmin	473..601	CDD:175975	52/139 (37%)
Syt17	NP_001390574.1	C2A_Synaptotagmin-15-17	186..314	CDD:176036	42/128 (33%)
		C2B_Synaptotagmin-17	323..457	CDD:176055	52/139 (37%)